{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T10:11:27Z","timestamp":1779358287692,"version":"3.51.4"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,1,21]],"date-time":"2013-01-21T00:00:00Z","timestamp":1358726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet. Med."],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:sec><jats:label\/><jats:p>Diabet. Med. 30, 233\u2013238 (2013)<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aims\u2003<\/jats:bold> To describe change in physical activity over 1\u2003year and associations with change in cardiovascular disease risk factors in a population with screen\u2010detected Type\u20032 diabetes.<\/jats:p><jats:p><jats:bold>Methods\u2003<\/jats:bold> Eight hundred and sixty\u2010seven individuals with screen\u2010detected diabetes underwent measurement of self\u2010reported physical activity, cardiovascular disease risk factors and modelled cardiovascular disease risk at baseline and 1\u2003year (<jats:italic>n<\/jats:italic>\u2003=\u2003736) in the ADDITION\u2010Cambridge trial. Multiple linear regression was used to quantify the association between change in different physical activity domains and cardiovascular disease risk factors at 1\u2003year.<\/jats:p><jats:p><jats:bold>Results\u2003<\/jats:bold> There was no change in self\u2010reported physical activity over 12\u2003months. Even relatively large changes in physical activity were associated with relatively small changes in cardiovascular disease risk factors after allowing for changes in self\u2010reported medication and diet. For every 30 metabolic equivalent\u2010h increase in recreational activity (equivalent to 10\u2003h\/brisk walking\/week), there was an average reduction of 0.1% in HbA<jats:sub>1c<\/jats:sub>  in men (95%\u2003CI \u22120.15 to \u22120.01, <jats:italic>P<\/jats:italic>\u2003=\u20030.021) and an average reduction of 2\u2003mmHg in systolic blood pressure in women (95%\u2003CI \u22124.0 to \u22120.05, <jats:italic>P<\/jats:italic>\u2003=\u20030.045).<\/jats:p><jats:p><jats:bold>Conclusions\u2003<\/jats:bold> Few associations were observed between change in different physical activity domains and cardiovascular disease risk factors in this trial cohort. Cardiovascular disease risk reduction appeared to be driven largely by factors other than changes in self\u2010reported physical activity in the first year following diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1464-5491.2012.03765.x","type":"journal-article","created":{"date-parts":[[2012,8,22]],"date-time":"2012-08-22T16:23:20Z","timestamp":1345652600000},"page":"233-238","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Changes in physical activity and modelled cardiovascular risk following diagnosis of diabetes: 1\u2010year results from the ADDITION\u2010Cambridge trial cohort"],"prefix":"10.1111","volume":"30","author":[{"given":"A.","family":"Barakat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. M.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. T.","family":"Prevost","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.\u2010L.","family":"Kinmonth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. J.","family":"Wareham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. J.","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. K.","family":"Simmons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,21]]},"reference":[{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc06-1317"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2004.05.024"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2010.334"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2010.380"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39474.922025.BE"},{"key":"e_1_2_10_7_2","volume-title":"Handbook for Vascular Risk Assessment, Risk Reduction and Risk Management","author":"National Screening Committee","year":"2008"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-9-136"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/1520-7560(200005\/06)16:3<164::AID-DMRR103>3.0.CO;2-R"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2010.03056.x"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60698-3"},{"key":"e_1_2_10_13_2","article-title":"Clinical Guidelines and Evidence for Type\u20032 Diabetes: Management of Blood Pressure","author":"McIntosh A","year":"2002","journal-title":"Sheffield: School of Health and Related Research (ScHARR)"},{"key":"e_1_2_10_14_2","article-title":"Clinical Guidelines and Evidence for Type\u20032 Diabetes: Lipids Management","author":"McIntosh A","year":"2002","journal-title":"Sheffield: School of Health and Related Research (ScHAAR)"},{"key":"e_1_2_10_15_2","article-title":"Clinical Guidelines and Evidence Review for Type\u20032 Diabetes: Management of Blood Glucose","author":"McIntosh A","year":"2001","journal-title":"Sheffield: School of Health and Related Research (ScHAAR)"},{"key":"e_1_2_10_16_2","first-page":"A170","article-title":"The Oxford Risk Engine: a cardiovascular risk calculator for individuals with or without Type\u20032 diabetes","volume":"56","author":"Coleman R","year":"2007","journal-title":"Diabetes"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/31.1.168"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60442-X"}],"container-title":["Diabetic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1464-5491.2012.03765.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1464-5491.2012.03765.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/j.1464-5491.2012.03765.x","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1464-5491.2012.03765.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T03:47:15Z","timestamp":1697600835000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1464-5491.2012.03765.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,21]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["10.1111\/j.1464-5491.2012.03765.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1464-5491.2012.03765.x","archive":["Portico"],"relation":{},"ISSN":["0742-3071","1464-5491"],"issn-type":[{"value":"0742-3071","type":"print"},{"value":"1464-5491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,21]]},"assertion":[{"value":"2013-01-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}