{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T08:09:47Z","timestamp":1773043787601,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2009,1,14]],"date-time":"2009-01-14T00:00:00Z","timestamp":1231891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Drug and Alcohol Review"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p> <jats:italic>\n            <jats:bold>Introduction and Aims.<\/jats:bold> Alcohol\u2010 and other drug\u2010use disorders have been found to be associated with mental disorders, however, complete characteristics of these comorbid mental disorders are not completely clear in early population based studies. This study aimed to explore the extent and profiles of comorbid mental disorders with alcohol\u2010 and other drug\u2010use disorders using a large inpatient dataset. <jats:bold>Methods.<\/jats:bold> The data source was the New South Wales (NSW) Inpatient Statistic Data Collection which collects the clinical data of hospital admissions in NSW, Australia. The data were coded using the International Classification of Diseases\u201410th Revision (ICD\u201010). The data were from 1 July 2005 to 30 June 2006 the Australian financial year and statistical analysis was performed using SAS. <jats:bold>Results.<\/jats:bold> Of 1\u2003592\u2003156 patients admitted, 91\u2003510 (6%) had at least one mental disorder diagnosis and 18\u2003283 (1.1%) had at least one alcohol\u2010 or other drug\u2010related diagnosis. Of these patients, an overall 9.6% had dual diagnoses. Comorbidity was nearly five times higher in alcohol\u2010 and other drug\u2010use disorders than in mental health disorders (52.4% vs. 10.5%). Comorbidity was higher in males than females (12% vs. 7.1%) and was the most common in patients aged from 20 to 49 regardless of sex. There was a significantly increased risk of developing a comorbid condition in all age groups above 10\u2003years. The most common mental health disorders were major depressive disorders, followed by dementia, anxiety and severe stress. Alcohol\u2010use disorder was the most common diagnosis, followed by cannabis and opioids. <jats:bold>Discussion and Conclusion.<\/jats:bold> This study shows the characteristics of comorbid mental and alcohol\u2010 or other drug\u2010use disorders. The study extends our understanding of issues addressed in previous population studies.<\/jats:italic>[Lai HMX, Huang QR. 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