{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T22:16:25Z","timestamp":1793052985533,"version":"4.5.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["vaajournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Anaesthesia and Analgesia"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1111\/j.1467-2995.2008.00430.x","type":"journal-article","created":{"date-parts":[[2008,12,12]],"date-time":"2008-12-12T05:38:38Z","timestamp":1229060318000},"page":"86-94","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Glomerular filtration rate after tramadol, parecoxib and pindolol following anaesthesia and analgesia in comparison with morphine in dogs"],"prefix":"10.1016","volume":"36","author":[{"given":"Kavitha","family":"Kongara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Chambers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig B","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/j.1467-2995.2008.00430.x_bib1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1191\/096813098668122984","article-title":"The clinical use of tramadol hydrochloride","volume":"5","author":"Bamigbade","year":"1998","journal-title":"Pain Rev"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib2","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1046\/j.1467-2995.2000.00024.x","article-title":"Evaluation of the analgesic properties of acepromazine maleate, oxymorphone, medetomidine and a combination of acepromazine\u2013oxymorphone","volume":"27","author":"Barnhart","year":"2000","journal-title":"Vet Anaesth Analg"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib3","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1097\/00000542-200208000-00004","article-title":"Efficacy and safety of intravenous parecoxib sodium in relieving acute post-operative pain following gynecologic laparotomy surgery","volume":"97","author":"Barton","year":"2002","journal-title":"Anesthesiology"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2460\/ajvr.1996.57.01.105","article-title":"Evaluation of a single injection method using iohexol for estimating glomerular filtration rate in cats and dogs","volume":"57","author":"Brown","year":"1996","journal-title":"Am J Vet Res"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib5","doi-asserted-by":"crossref","first-page":"271","DOI":"10.3109\/00365517209084290","article-title":"A simple method for the determination of glomerular filtration rate","volume":"30","author":"Brfchner-Mortensen","year":"1972","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib6","first-page":"A868","article-title":"Central nervous system penetration of oral rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, in rats","volume":"95","author":"Buvanendran","year":"2001","journal-title":"Anesthesiology"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib7","doi-asserted-by":"crossref","first-page":"A465","DOI":"10.1097\/00000542-200209002-00465","article-title":"Blood\u2013brain barrier penetration of oral rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, in dogs","volume":"96","author":"Buvanendran","year":"2002","journal-title":"Anesthesiology"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib8","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1365-2885.1995.tb00573.x","article-title":"The effects of opioid and a2 adrenergic blockade on non-steroidal anti-inflammatory drug analgesia in sheep","volume":"18","author":"Chambers","year":"1995","journal-title":"J Vet Pharmacol Ther"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib9","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1093\/bja\/aeh268","article-title":"Role of \u03b2-Blockade in anaesthesia and postoperative pain management after hysterectomy","volume":"93","author":"Chia","year":"2004","journal-title":"Br J Anaesth"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib10","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0304-3959(00)00299-2","article-title":"Pindolol, a beta-adrenoceptor blocker\/5-hydroxytryptamine (1A\/1B) antagonist, enhances the analgesic effect of tramadol","volume":"88","author":"Corrales","year":"2000","journal-title":"Pain"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib11","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.2460\/ajvr.2004.65.1384","article-title":"Effect of meloxicam and carprofen on renal function when administered to healthy dogs prior to anaesthesia and painful stimulation","volume":"65","author":"Crandell","year":"2004","journal-title":"Am J Vet Res"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib12","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1097\/00000542-200502000-00026","article-title":"Central nervous system concentrations of cyclooxygenase-2 inhibitors in humans","volume":"102","author":"Dembo","year":"2005","journal-title":"Anesthesiology"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib13","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1097\/00000539-200109000-00036","article-title":"The injectable cyclooxygenase-2-specific inhibitor parecoxib sodium has analgesic efficacy when administered pre-operatively","volume":"93","author":"Desjardins","year":"2001","journal-title":"Anesth Analg"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib14","series-title":"Textbook of Veterinary Internal Medicine","first-page":"1706","article-title":"Clinical approach and laboratory evaluation of renal disease","author":"DiBartola","year":"1995"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib15","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/S0306-4522(99)00164-5","article-title":"The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an up-regulation of cyclo-oxygenase-2 in the spinal cord","volume":"93","author":"Ebersberger","year":"1999","journal-title":"Neuroscience"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib16","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1111\/j.1939-1676.2001.tb02331.x","article-title":"Relationship between plasma iohexol clearance and urinary exogenous creatinine clearance in dogs","volume":"15","author":"Finco","year":"2001","journal-title":"J Vet Intern Med"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib17","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/j.1748-5827.2000.tb03151.x","article-title":"Effect of NSAID administration on creatinine clearance in healthy dogs undergoing anaesthesia and surgery","volume":"41","author":"Forsyth","year":"2000","journal-title":"J Small Anim Pract"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib18","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1056\/NEJM198304213081606","article-title":"Drug therapy. Pindolol: a new beta-adrenoceptor antagonist with partial agonist activity","volume":"308","author":"Frishman","year":"1983","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib19","first-page":"57","article-title":"Plasma clearance of nonradioactive iohexol as a measure of glomerular filtration rate","volume":"62","author":"Gaspari","year":"1995","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib20","series-title":"Lumb and Jones\u2019 Veterinary Anaesthesia","first-page":"785","article-title":"Renal disease","author":"Greene","year":"1996"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib21","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1080\/01652176.1995.9694584","article-title":"The use of iohexol to measure glomerular filtration rate in the dog","volume":"17","author":"Heiene","year":"1995","journal-title":"Vet Q"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib22","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/j.1939-1676.1998.tb02143.x","article-title":"Pharmacokinetic aspects of measurement of glomerular filtration rate in the dog: a review","volume":"12","author":"Heiene","year":"1998","journal-title":"J Vet Intern Med"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib23","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.1939-1676.1999.tb02215.x","article-title":"The relationship between some plasma clearance methods for estimation of glomerular filtration rate in dogs with pyometra","volume":"13","author":"Heiene","year":"1999","journal-title":"J Vet Intern Med"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib24","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1161\/01.RES.33.4.428","article-title":"Contribution of intrarenal generation of prostaglandin to autoregulation of renal blood flow in the dog","volume":"33","author":"Herbaczynska-Cedro","year":"1973","journal-title":"Circ Res"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib25","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/BF01855043","article-title":"Renal function in conscious dogs: potential effect of gender on measurement","volume":"189","author":"Izzat","year":"1989","journal-title":"Res Exp Med"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib26","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1136\/vr.155.21.667","article-title":"Comparison of the analgesic effects of meloxicam and carprofen administered pre-operatively to dogs undergoing orthopaedic surgery","volume":"155","author":"Laredo","year":"2004","journal-title":"Vet Rec"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib27","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0304-3959(97)00141-3","article-title":"Post-operative central hypersensitivity and pain: the pre-emptive value of pethidine for ovariohysterectomy","volume":"73","author":"Lascelles","year":"1997","journal-title":"Pain"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib28","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.2527\/1998.7641216x","article-title":"Statistical analysis of repeated measures data using SAS procedures","volume":"76","author":"Littell","year":"1998","journal-title":"J Anim Sci"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib29","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.2460\/ajvr.2000.61.1501","article-title":"Effect of administration of nonsteroidal anti-inflammatory drugs before surgery on renal function in clinically normal dogs","volume":"61","author":"Lobetti","year":"2000","journal-title":"Am J Vet Res"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib30","doi-asserted-by":"crossref","first-page":"121","DOI":"10.2460\/ajvr.2000.61.121","article-title":"Effects of general anesthesia and surgery on renal function in healthy dogs","volume":"61","author":"Lobetti","year":"2000","journal-title":"Am J Vet Res"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib31","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S0022-3565(25)10314-5","article-title":"Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat","volume":"263","author":"Malmberg","year":"1992","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib32","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1046\/j.1467-2995.2003.00090.x","article-title":"A comparison of preoperative tramadol and morphine for the control of early postoperative pain in canine ovariohysterectomy","volume":"30","author":"Mastrocinque","year":"2003","journal-title":"Vet Anaesth Analg"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib33","doi-asserted-by":"crossref","first-page":"882","DOI":"10.2460\/ajvr.2001.62.882","article-title":"Safety and efficacy of preoperative administration of meloxicam compared with that of ketoprofen and butorphanol in dogs undergoing abdominal surgery","volume":"62","author":"Mathews","year":"2001","journal-title":"Am J Vet Res"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib34","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/0034-5288(95)90067-5","article-title":"Estimation of glomerular filtration rate in dogs with 99M- Tc-DTPA and iohexol","volume":"58","author":"Moe","year":"1995","journal-title":"Res Vet Sci"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib35","doi-asserted-by":"crossref","first-page":"885","DOI":"10.2460\/ajvr.1997.58.08.885","article-title":"Cardiopulmonary effects of sevoflurane, compared with halothane, enflurane, and isoflurane in dogs","volume":"58","author":"Mutoh","year":"1997","journal-title":"Am J Vet Res"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib36","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1097\/00000539-200203000-00026","article-title":"Tramadol has no effect on cortical renal blood flow \u2013 despite increased serum catecholamine levels \u2013 in anaesthetized rats: implications for analgesia in renal insufficiency","volume":"94","author":"Nagaoka","year":"2002","journal-title":"Anesth Analg"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib37","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0014-2999(98)00868-1","article-title":"Anti-inflammatory and analgesic effects of a novel pyrazole derivative FR 140423","volume":"365","author":"Ochi","year":"1999","journal-title":"Eur J Pharmacol"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib38","first-page":"6","article-title":"Renal complications associated with use of NSAIDS","volume":"43","author":"Palmer","year":"1995","journal-title":"J Invest Med"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib39","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1517\/14740338.1.1.53","article-title":"COX-2 selective inhibitors: analysis of the renal effects","volume":"1","author":"Perazella","year":"2002","journal-title":"Expert Opin Drug Saf"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib40","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S1090-3801(98)90032-5","article-title":"Interactions in the antinociceptive effect of tramadol in mice: an isobolographic analysis","volume":"2","author":"Pinardi","year":"1998","journal-title":"Eur J Pain"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib41","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0022-3565(25)11227-5","article-title":"Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an \u2018Atypical\u2019 opioid analgesic","volume":"260","author":"Raffa","year":"1992","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib42","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1046\/j.1471-4159.1997.68062593.x","article-title":"Preferential potentiation of the effects of serotonin uptake inhibitors by 5-HT1A receptor antagonist in the dorsal raphe pathway: role of somatodendritic autoreceptors","volume":"68","author":"Romero","year":"1997","journal-title":"J Neurochem"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib43","first-page":"1269","article-title":"Iohexol determination by direct injection of serum on the HPLC column","volume":"16","author":"Shihabi","year":"1993","journal-title":"J Liq Chromatogr"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib45","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1136\/vr.148.14.441","article-title":"Analgesic effects in dogs of carprofen and pethidine together compared with the effects of either drug alone","volume":"148","author":"Slingsby","year":"2001","journal-title":"Vet Rec"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib46","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1053\/rvsc.2001.0467","article-title":"Use of a new finger-mounted device to compare mechanical nociceptive thresholds in cats given pethidine or no medication after castration","volume":"70","author":"Slingsby","year":"2001","journal-title":"Res Vet Sci"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib47","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1021\/jm000069h","article-title":"Parecoxib sodium: a potent and selective inhibitor of COX-2 for parenteral administration","volume":"43","author":"Talley","year":"2000","journal-title":"J Med Chem"},{"key":"10.1111\/j.1467-2995.2008.00430.x_bib48","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1080\/00498250110057378","article-title":"Metabolism of the analgesic drug, tramadol hydrochloride, in rat and dog","volume":"31","author":"Wu","year":"2001","journal-title":"Xenobiotica"}],"container-title":["Veterinary Anaesthesia and Analgesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298716306304?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298716306304?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T02:53:11Z","timestamp":1761447191000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1467298716306304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S1467298716306304"],"URL":"https:\/\/doi.org\/10.1111\/j.1467-2995.2008.00430.x","relation":{},"ISSN":["1467-2987"],"issn-type":[{"value":"1467-2987","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Glomerular filtration rate after tramadol, parecoxib and pindolol following anaesthesia and analgesia in comparison with morphine in dogs","name":"articletitle","label":"Article Title"},{"value":"Veterinary Anaesthesia and Analgesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/j.1467-2995.2008.00430.x","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}