{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:56:54Z","timestamp":1774573014205,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,4,15]],"date-time":"2012-04-15T00:00:00Z","timestamp":1334448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Although<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected patients are at greater risk of presenting with ischaemic necrosis of the femoral head, there have been concerns about whether total hip arthroplasty (<jats:styled-content style=\"fixed-case\">THA<\/jats:styled-content>) may have worse outcomes than expected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From the<jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>rthopedic and<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>rauma<jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>urgery database we identified all patients who had undergone<jats:styled-content style=\"fixed-case\">THA<\/jats:styled-content>because of ischaemic necrosis of the femoral head from<jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2001 until<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch 2010. Patient's diagnosis of<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>infection was confirmed at the time of arthroplasty by cross\u2010matching with the<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>unit database. For every<jats:styled-content style=\"fixed-case\">THA<\/jats:styled-content>in<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected patients, two<jats:styled-content style=\"fixed-case\">THA<\/jats:styled-content>s in patients not known to be<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected, with the same diagnosis of ischaemic necrosis of the femoral head and having undergone surgery over the same period, were randomly selected.<jats:styled-content style=\"fixed-case\">THA<\/jats:styled-content>s were compared in<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010 and non\u2010<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected patients for surgical procedure, in\u2010patient stay and long\u2010term prognosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 18<jats:styled-content style=\"fixed-case\">THA<\/jats:styled-content>s in 13<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected patients and 36<jats:styled-content style=\"fixed-case\">THA<\/jats:styled-content>s in 27 non\u2010<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected patients. No significant differences were observed in the mean time spent in surgery (106<jats:italic>vs.<\/jats:italic>109 minutes, respectively;<jats:italic>P<\/jats:italic>\u2009=\u20090.66), the need for red cell transfusion (1<jats:italic>vs.<\/jats:italic>4, respectively;<jats:italic>P<\/jats:italic>\u2009=\u20090.48) or the mean duration of hospitalization (7.8<jats:italic>vs.<\/jats:italic>9.4 days, respectively;<jats:italic>P<\/jats:italic>\u2009=\u20090.48). The two groups showed similar postoperative functional results, which were maintained until the end of the follow\u2010up period (median 3.3 years in the HIV\u2010positive group and 5.8 years in the HIV\u2010negative group).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study suggests that the outcome of<jats:styled-content style=\"fixed-case\">THA<\/jats:styled-content>in<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive patients is not worse than that of<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010negative patients, although future research on larger numbers of patients is required to confirm this.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1468-1293.2012.01017.x","type":"journal-article","created":{"date-parts":[[2012,4,16]],"date-time":"2012-04-16T04:15:20Z","timestamp":1334549720000},"page":"623-629","source":"Crossref","is-referenced-by-count":30,"title":["Total hip arthroplasty 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