{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T04:22:02Z","timestamp":1786681322401,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,9,24]],"date-time":"2012-09-24T00:00:00Z","timestamp":1348444800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2013,3]]},"abstract":"Objectives<\/jats:title>The aim of the study was to determine the seroprevalence and epidemiological features of hepatitis B<\/jats:styled-content> virus (HBV<\/jats:styled-content>) and hepatitis C<\/jats:styled-content> virus (HCV<\/jats:styled-content>) infection among patients newly diagnosed with HIV<\/jats:styled-content>\/AIDS<\/jats:styled-content> in C<\/jats:styled-content>hina.<\/jats:p><\/jats:sec>Methods<\/jats:title>Two thousand and forty patients newly diagnosed with HIV<\/jats:styled-content>\/AIDS<\/jats:styled-content> from 10 provinces in C<\/jats:styled-content>hina were selected during 2009 to 2010. Serum samples obtained from each individual were screened for HBV<\/jats:styled-content> and HCV<\/jats:styled-content> serum markers [HBV<\/jats:styled-content> surface antigen (HBsAg<\/jats:styled-content>), HBV<\/jats:styled-content> surface antibody (HBsAb<\/jats:styled-content>), HBV<\/jats:styled-content> envelope antigen (HBeAg<\/jats:styled-content>), HBV<\/jats:styled-content> envelope antibody (HBeAb<\/jats:styled-content>), HBV<\/jats:styled-content> core antibody (HBcAb<\/jats:styled-content>) and HCV<\/jats:styled-content> antibody (HCVAb<\/jats:styled-content>)]; liver function tests were also performed. Demographics and medical histories were collected.<\/jats:p><\/jats:sec>Results<\/jats:title>Of the 2040 patients, 741 (36.3%) were positive for at least one HBV<\/jats:styled-content> and HCV<\/jats:styled-content> serum marker; 300 (14.71%) were HCVAb<\/jats:styled-content> positive, and 248 (12.16%) were isolated HCVAb<\/jats:styled-content> positive; 222 (10.9%) were positive for HBsAg<\/jats:styled-content>; 19 (0.93%) were positive for both HBsAg<\/jats:styled-content> and HCVAb<\/jats:styled-content>. The highest prevalence of HBsAg positivity was found in G<\/jats:styled-content>uangxi (15.31%), followed by G<\/jats:styled-content>uangdong (15.19%) and S<\/jats:styled-content>hanghai (14.36%). The highest prevalence of HCVAb<\/jats:styled-content> positivity was found in Xinjiang (43.18%), followed by H<\/jats:styled-content>enan (39.06%) and Y<\/jats:styled-content>unnan (27.36%). The proportion of patients with abnormal liver function in patients positive for HCVAb<\/jats:styled-content> and\/or HBsAg<\/jats:styled-content> was significantly higher than that in those who were negative for both HCVAb<\/jats:styled-content> and HBsAg<\/jats:styled-content> (P<\/jats:styled-content><\/jats:italic>\u2009<\u20090.001).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The seroprevalence of HBV<\/jats:styled-content> and HCV<\/jats:styled-content> among patients newly diagnosed with HIV<\/jats:styled-content>\/AIDS<\/jats:styled-content> in C<\/jats:styled-content>hina is high. HBsAg<\/jats:styled-content> and HCVAb<\/jats:styled-content> positivity prevalences were found to vary significantly in different provinces in C<\/jats:styled-content>hina. Patients newly diagnosed with HIV<\/jats:styled-content>\/AIDS<\/jats:styled-content> and coinfected with HBV<\/jats:styled-content> and HCV<\/jats:styled-content> are at higher risk of abnormal liver function. It is necessary to routinely screen for HBV<\/jats:styled-content> and HCV<\/jats:styled-content> infection among patients newly diagnosed with HIV<\/jats:styled-content>\/AIDS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1468-1293.2012.01048.x","type":"journal-article","created":{"date-parts":[[2012,9,24]],"date-time":"2012-09-24T04:17:03Z","timestamp":1348460223000},"page":"167-175","source":"Crossref","is-referenced-by-count":14,"title":["Serological survey of viral hepatitis markers among newly diagnosed patients with HIV<\/scp>\/AIDS<\/scp> in C<\/scp>hina"],"prefix":"10.1111","volume":"14","author":[{"given":"YZ","family":"Shen","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Shanghai Public Health Clinical Center Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ZY","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Shanghai Public Health Clinical Center Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TK","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Shanghai Public Health Clinical Center Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XY","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Shanghai Public Health Clinical Center Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Shanghai Public Health Clinical Center Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Shanghai Public Health Clinical Center Fudan University Shanghai 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