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Of 17 consecutive patients with Guillain\u2013Barr\u00e9 syndrome (GBS), 13 patients (six females; mean age 50\u2003\u00b1\u200324\u2003years) with AIDP were investigated. Clinical status was evaluated according to Hughes\u2019 score, and electrophysiological tests were performed within 2\u2003weeks from disease onset. <jats:italic>Helicobacter pylori<\/jats:italic> infection was detected histologically and serum <jats:italic>H. pylori<\/jats:italic>\u2010specific IgG antibodies were analysed by ELISA. Twenty asymptomatic patients (12 females; mean age 63\u2003\u00b1\u20038\u2003years), undergoing upper gastrointestinal endoscopy for investigation of mild iron deficiency anaemia, served as controls. <jats:italic>Helicobacter pylori<\/jats:italic> was found in 12 of 13 AIDP patients (92%), and in 10 of 20 controls (50%), (<jats:italic>P<\/jats:italic>\u2003=\u20030.02). Electrophysiological studies showed demyelination in all AIDP patients. High levels of anti\u2010<jats:italic>H. pylori<\/jats:italic> IgG antibodies correlated with advanced clinical status. Five of seven AIDP patients with high levels of anti\u2010<jats:italic>H. pylori<\/jats:italic> IgG antibodies had delayed F\u2010wave latencies, indicating affection of proximal segments of peripheral nerves. <jats:italic>Helicobacter pylori<\/jats:italic> infection seems to be more frequent in AIDP patients. Anti\u2010<jats:italic>H. pylori<\/jats:italic> titre might reflect advanced clinical status. Anti\u2010<jats:italic>H. pylori<\/jats:italic> IgG antibodies are also associated with involvement of the proximal parts of peripheral nerves in AIDP.<\/jats:p>","DOI":"10.1111\/j.1468-1331.2004.00977.x","type":"journal-article","created":{"date-parts":[[2005,1,29]],"date-time":"2005-01-29T08:49:28Z","timestamp":1106988568000},"page":"139-143","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["Association between <i>Helicobacter pylori<\/i> infection and acute inflammatory demyelinating 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