{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:57:45Z","timestamp":1780052265922,"version":"3.53.1"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,1,23]],"date-time":"2007-01-23T00:00:00Z","timestamp":1169510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2007,2]]},"abstract":"<jats:p>Several analyses of the neurological features of Beh\u00e7et's disease (BD) have concluded that there are significant racial differences in its clinical expression. Other series, however, failed to elicit such differences. We aimed to describe in this retrospective survey the frequency, nature and relationship to systemic disease of the neurological features in a cohort of BD patients of Caucasian origin. We searched hospital records from nine District General or Regional Centre hospitals in south\u2010west Great Britain and identified 22 individuals of Caucasian ethnic origin with neuro\u2010BD, with a mean of 10\u2003years follow\u2010up per patient \u2013 the largest \u2018western\u2019 case series with the longest period of follow\u2010up reported. We found that presentation with neurological features was commoner in our patients (23%) than Middle Eastern series (3\u201310%). Seizures (27%) were likewise commoner (0\u20135%), as was optic neuritis (9% compared with 1\u20132%). Two patients developed movement disorders (chorea and parkinsonism), which have only been rarely reported. Of further clinical significance, we noted that non\u2010neuropsychiatric features: oral ulceration, intraocular inflammation and skin lesions \u2013 were virtually always present or exacerbated during neurological complications. Ethnicity \u2013 or conceivably environment \u2013 may play a significant role in the manifestation of neurological BD.<\/jats:p>","DOI":"10.1111\/j.1468-1331.2006.01613.x","type":"journal-article","created":{"date-parts":[[2007,1,23]],"date-time":"2007-01-23T09:31:07Z","timestamp":1169544667000},"page":"174-180","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":78,"title":["Neuro\u2010Beh\u00e7et's disease in Caucasians: a study of 22 patients"],"prefix":"10.1111","volume":"14","author":[{"given":"F. G.","family":"Joseph","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. 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