{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:14:44Z","timestamp":1760955284066},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p><jats:bold>Background:\u2002<\/jats:bold> This study evaluated the usefulness of MR angiography (MRA)\u2013diffusion\u2010weighted imaging (DWI) mismatch in neuroendovascular therapy over 3\u2003h after onset of acute cerebral infarction.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> The subjects were 14 cases (age, 73\u2003\u00b1\u20038.4\u2003years) who had an anterior circulation deficit on DWI\/MRA on arrival and underwent neuroendovascular therapy over 3\u2003h after onset. MRA\u2010DWI mismatch (MDM) (+) was defined as \u2018major artery lesion (+) and diffusion\u2010weighted image\u2010Alberta Stroke Program Early CT Score (DWI\u2010ASPECTS) \u22656\u2019; MDM (\u2212) was defined as \u2018major artery lesion (+) and DWI\u2010ASPECTS &lt;6\u2019.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Reperfusion was achieved in nine of 14 patients (64%) undergoing neuroendovascular therapy. Within the reperfusion group, in the five MDM (+) patients and the four MDM (\u2212) patients, the outcome was a favorable clinical response in the MDM (+) group. The modified Rankin Scale (mRS) scores after 90\u2003days were 0\u20132 in 3 (60%) and 3\u20136 in 2 (40%) of the MDM (+) group patients and 0\u20132 in 0 (0%) and 3\u20136 in 4 (100%) of the MDM (\u2212) group patients. In the MDM (+) group, a good outcome was achieved. However, the number of cases was small, so this was not a significant difference. Within the non\u2010reperfusion group, in the three MDM (+) patients and the two MDM (\u2212) patients, the mRS scores after 90\u2003days were 0\u20132 in 1 (33%) and 3\u20136 in 2 (67%) of the MDM (+) group patients and 0\u20132 in 0 (0%) and 3\u20136 in 2 (100%) of the MDM (\u2212) group patients. In both groups, the outcome was poor.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> With neuroendovascular therapy, a good outcome with reperfusion was achieved in the MDM (+) group compared to the MDM (\u2212) group. This suggests that the presence or absence of MDM may be useful in determining prognosis after reperfusion.<\/jats:p>","DOI":"10.1111\/j.1468-1331.2011.03444.x","type":"journal-article","created":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T12:37:48Z","timestamp":1306931868000},"page":"114-120","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Usefulness of MRA\u2010DWI mismatch in neuroendovascular therapy for acute cerebral 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