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The antiganglioside anti\u2010GQ1b IgG antibody has a role in the pathogenesis of the syndrome, especially of ophthalmoplegia. The presence of this antibody in the serum can be identified in over 80% of the patients, peaking in the first week, whereas albuminocytological dissociation in the cerebrospinal fluid (CSF) appears later. The most consistent electrophysiological findings in MFS are reduced sensory nerve action potentials and absent H reflexes. More variability is seen with F waves and various investigations involving cranial structures. Although there are usually no abnormalities in MFS by routine neuroimaging, in a few cases, contrast enhancement of nerve roots and signs of central nervous system involvement were described supporting the hypothesis of an anti\u2010GQ1b\u2010syndrome, a continuum involving GBS, MFS, and Bickerstaff\u2019s brainstem encephalitis. Owing to the lack of randomized trials, treatments used for GBS (intravenous immunoglobulin and plasmapheresis) are usually applied, although from retrospective analyses, the outcome was similar between treated and untreated subjects. The outcome of MFS is usually good with case fatality of &lt;\u20035%. In the few autopsy cases, macroscopic abnormalities were generally not seen in the nervous system. Microscopic examination of the peripheral nervous system (including cranial nerves) showed segmental demyelination with minimal perivascular infiltration with normal spinal cord and brain stem.<\/jats:p>","DOI":"10.1111\/j.1468-1331.2011.03445.x","type":"journal-article","created":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T12:40:30Z","timestamp":1306932030000},"page":"15","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":75,"title":["Miller Fisher syndrome: brief overview and update with a focus on electrophysiological findings"],"prefix":"10.1111","volume":"19","author":[{"given":"Z.","family":"Ar\u00e1nyi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Kov\u00e1cs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Sipos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Bereczki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,6]]},"reference":[{"key":"e_1_2_12_2_2","first-page":"472","article-title":"Note sur la paralysie ascendante aigue","volume":"6","author":"Landry O","year":"1859","journal-title":"Gazette Hebdomadaire de Medicin"},{"key":"e_1_2_12_3_2","first-page":"1462","article-title":"Sur un syndrome de radiculo\u2010nevrite hyperalbuminose du liquide cephalorachidien sans reaction cellulaire","volume":"40","author":"Guillain G","year":"1916","journal-title":"Bull Soc Med Hop Paris"},{"key":"e_1_2_12_4_2","first-page":"601","article-title":"Peripheral neuritis","volume":"39","author":"Collier J","year":"1932","journal-title":"Edinburgh Med J"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM195607122550201"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1986.00520110044012"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1994.00540190051014"},{"key":"e_1_2_12_8_2","first-page":"611","article-title":"Variants of Guillain\u2010Barr\u00e9 syndrome: Miller Fisher syndrome, facial diplegia and multiple cranial nerve palsies","volume":"14","author":"Shuaib A","year":"1987","journal-title":"Can J Neurol Sci"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000184748"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20835"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000008201"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2009.02951.x"},{"key":"e_1_2_12_13_2","first-page":"471","article-title":"Miller\u2010Fisher syndrome at king Chulalongkorn memorial hospital","volume":"92","author":"Lolekha P","year":"2009","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_12_14_2","doi-asserted-by":"publisher","DOI":"10.1157\/13058172"},{"key":"e_1_2_12_15_2","first-page":"311","article-title":"Guillain\u2010Barre syndrome. 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