{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:44:03Z","timestamp":1792806243721,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,9,26]],"date-time":"2011-09-26T00:00:00Z","timestamp":1316995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:p><jats:bold>Background and purpose:\u2002<\/jats:bold> Despite the absence of robust scientific evidence, it is today generally accepted that the acute headache typical for intracranial infections can develop into permanent headache complaints. This widespread concept was explored in the first, large, longitudinal, population\u2010based study.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Data on confirmed exposure to intracranial infections amongst all adult inhabitants in a geographical area during a 20\u2010year period were assembled from hospital records. Surviving individuals were later invited to the third Nord\u2010Tr\u00f8ndelag Health Survey (HUNT 3), where 39\u2003690 (42%) of 94\u2003194 invited inhabitants aged \u226520\u2003years responded to a validated headache questionnaire. Using logistic regression, the 1\u2010year prevalence of headache and its subtypes according to the diagnostic criteria of the International Headache Society was assessed and compared between those with and without previous confirmed intracranial infection. Age and sex were used as covariates.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Overall, 43 participants were identified with earlier intracranial infection, whereof three had more than one infection: bacterial meningitis (<jats:italic>n<\/jats:italic>\u2003=\u200319), lymphocytic meningitis (<jats:italic>n<\/jats:italic>\u2003=\u200318), encephalitis (<jats:italic>n<\/jats:italic>\u2003=\u20039), and brain abscess (<jats:italic>n<\/jats:italic>\u2003=\u20031).The mean interval from infection to participation in HUNT 3 was 11.2 (range 1.5\u201319.7) years. There was no significant increase in the prevalence of headache (OR 1.10, 95% CI 0.58\u20132.07), its subtypes (migraine, or tension\u2010type headache), or chronic daily headache (OR 1.85, 95% CI 0.45\u20137.68) amongst participants with previous intracranial infection compared with the surrounding population.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> This study challenges the existence of chronic post\u2010bacterial meningitis headache and does not indicate the presence of other long\u2010term headaches induced by intracranial infection.<\/jats:p>","DOI":"10.1111\/j.1468-1331.2011.03525.x","type":"journal-article","created":{"date-parts":[[2011,9,28]],"date-time":"2011-09-28T01:14:08Z","timestamp":1317172448000},"page":"324-331","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["No increase in headache after previous intracranial infections: a historical cohort study (HUNT)"],"prefix":"10.1111","volume":"19","author":[{"given":"M.","family":"Linde","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. 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