{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:15:38Z","timestamp":1785842138327,"version":"3.56.0"},"reference-count":58,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,11,19]],"date-time":"2004-11-19T00:00:00Z","timestamp":1100822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2005,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Mucosal lichen planus of the vulva is a rare but increasingly recognized condition. It has potentially severe complications such as fusion of the labia and vagina; the risk of developing squamous cell carcinoma (SCC) may be increased. An association between hepatitis B and C infection and skin or oral lichen planus appears to exist in certain geographical areas.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> To investigate the course of mucosal vulval lichen planus, its response to treatment and associated laboratory features.<\/jats:p><jats:p><jats:bold>Subjects and methods\u2002<\/jats:bold> Forty\u2010four women with mucosal vulval lichen planus were studied between 1997 and 2000 and laboratory data were collected.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Thirty of 44 patients had additional oral lesions, only nine had cutaneous findings compatible with lichen planus. We did not find an association with antibodies to hepatitis B or C virus in this British study population. All women were treated with potent to very potent topical corticosteroids; however, in the majority of patients symptoms persisted. In seven\u00a0(16%) patients vulval lichen planus was in remission after a disease duration between 2 and 18\u00a0years (mean 10.6\u00a0years). One patient developed a vulval SCC.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Screening for hepatitis\u00a0B and C in women with mucosal vulval lichen planus in the UK seems unnecessary. We recommend long\u2010term follow\u2010up, and that all non\u2010healing ulcerative and papular lesions should be biopsied.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2004.01167.x","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T18:38:35Z","timestamp":1114627115000},"page":"301-307","source":"Crossref","is-referenced-by-count":72,"title":["Mucosal vulval lichen planus: outcome, clinical and laboratory features"],"prefix":"10.1111","volume":"19","author":[{"given":"G","family":"Kirtschig","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SH","family":"Wakelin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Wojnarowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,3,31]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"1899","volume-title":"Textbook of Dermatology","author":"Black MM","year":"1998"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1988.tb02376.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1991.tb00130.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1992.tb02663.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840360622"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2000.8533"},{"key":"e_1_2_6_8_2","first-page":"57","article-title":"Vulvo\u2013vagino\u2013gingival syndrome. 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