{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T04:01:01Z","timestamp":1780632061507,"version":"3.54.1"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,11,22]],"date-time":"2005-11-22T00:00:00Z","timestamp":1132617600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Dermographism or \u2018simple\u2019 dermographism, which has been noted in about 1.5% to 5% of healthy individuals, is regarded as a normal physiological phenomenon. However, in symptomatic dermographism (SD), even light pressure or rubbing from clothes may provoke widespread weal\u2010and\u2010flare reactions with itching and burning. It is one of the dermatologic diseases that negatively impacts quality of life.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> We aimed to reveal triggering factors and\/or associated clinical conditions in patients with SD.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Forty patients (28 women and 12 men) with SD whose ages varied between 7 and 65 (30.3\u00a0\u00b1\u00a010.7) participated in the study. Patients having chronic idiopathic urticaria, other types of physical urticaria and cutaneous\/systemic mastocytosis were excluded. The diagnosis of SD was confirmed by stroking the skin of the back with a tongue blade. This procedure elicited within minutes a linear weal with a flare and severe itching. In light of the history, physical examination, skin prick test (SPT) with aeroallergens and laboratory results, a possible relationship of certain triggering factors and\/or associated diseases (psychic factors, atopy, thyroid diseases, diabetes, menopause, infectious, systemic or malignant diseases, history of scabies, and history of drug reaction) to SD were investigated.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> The duration of SD varied between 10\u00a0days and 10\u00a0years (mean: 20.8\u00a0months). Psychic factors were found to play the initial triggering role in 12 patients (30%). Five patients (12.50%) were atopic, and they had SPT reactivity to house dust mites. Three female patients (7.50%) defined that their complaints began following drug\u2010induced urticarial rash. Two patients (5%) had hyperthyroidism, and one of the patients with SD of 1\u2010month duration had type\u2010II diabetes mellitus. A female patient defined that her complaints began during the onset of menopausal period. SD was observed with scabies in one patient; and after poststreptococcal glomerulonephritis in a 7\u2010year\u2010old girl. No autoimmune, malignant or other systemic diseases were found in patients with SD.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Contrary to commonly held opinion, SD may be associated with some diseases and\/or triggered by some conditions. In this study, a close temporal relationship between the appearance of SD and psychic factors, drug reactions and scabies was documented. The relation between SD and atopy, hyperthyroidism, diabetes mellitus, menopause and glomerulonephritis seemed unclear.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2005.01372.x","type":"journal-article","created":{"date-parts":[[2005,11,22]],"date-time":"2005-11-22T14:30:57Z","timestamp":1132669857000},"page":"58-62","source":"Crossref","is-referenced-by-count":41,"title":["Evaluation of patients with symptomatic dermographism"],"prefix":"10.1111","volume":"20","author":[{"given":"O","family":"Ta\u015fkapan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Harmanyeri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,22]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-97931-6"},{"key":"e_1_2_5_3_2","first-page":"1411","volume-title":"Dermatology in General Medicine","author":"Soter NA","year":"1999"},{"key":"e_1_2_5_4_2","first-page":"580","volume-title":"Allergy","author":"Kaplan AP","year":"1997"},{"key":"e_1_2_5_5_2","first-page":"2128","volume-title":"Textbook of Dermatology","author":"Kobza\u2010Black A","year":"1998"},{"key":"e_1_2_5_6_2","first-page":"195","volume-title":"Allergic Skin Disease","author":"Lawlor EF","year":"2000"},{"key":"e_1_2_5_7_2","first-page":"167","volume-title":"Andrew's Diseases of the Skin","author":"Odom RB","year":"2000"},{"key":"e_1_2_5_8_2","first-page":"166","article-title":"Prevalence of dermographism in children","volume":"10","author":"Martorell A","year":"2000","journal-title":"J Invest All Clin Immunol"},{"key":"e_1_2_5_9_2","first-page":"174","volume-title":"Allergic Skin Disease","author":"Greaves MW","year":"2000"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1995.tb06916.x"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000237648"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(93)70273-V"},{"key":"e_1_2_5_13_2","first-page":"148","article-title":"Dermographism: an adverse effect of atorvastatin","volume":"14","author":"Adcock BB","year":"2001","journal-title":"J Am Board Fam Pract"},{"key":"e_1_2_5_14_2","first-page":"32","article-title":"Psychic factors as a trigger in factitial urticaria and urticaria with positive dermographism [Abstract]","volume":"56","author":"Anliker MD","year":"2001","journal-title":"Allergy"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2005.01372.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2005.01372.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T22:31:13Z","timestamp":1697063473000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2005.01372.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11,22]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["10.1111\/j.1468-3083.2005.01372.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2005.01372.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,11,22]]}}}