{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T20:43:42Z","timestamp":1766868222659},"reference-count":43,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,1,4]],"date-time":"2006-01-04T00:00:00Z","timestamp":1136332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives\u2002<\/jats:bold> The aim of this study has been to evaluate patients with tinea pedis for their demographic data and attitudes affecting the treatment of disease, and to compare the <jats:italic>in vitro<\/jats:italic> activity of 10 antifungal agents and to relate them to their <jats:italic>in vivo<\/jats:italic> activity.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Patients with positive mycological examination were enrolled in the study, and a questionnaire comprised of 22 questions was administered. A mycological culture was carried out for each specimen. The antifungal susceptibility of the subcultured species was determined for griseofulvin, terbinafine, ciclopiroxolamine, fluconazole, ketoconazole, itraconazole, bifonazole, sulconazole, oxiconazole and miconazole with microdilution.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Mycological cultures were carried out from 59 patients and there were 35 positive cultures (59.3%). The dermatophytes were <jats:italic>Trichophyton rubrum<\/jats:italic> (<jats:italic>n<\/jats:italic>\u00a0=\u00a025) and <jats:italic>Trichophyton mentagrophytes<\/jats:italic> (<jats:italic>n<\/jats:italic>\u00a0=\u00a03). The yeasts were <jats:italic>Candida albicans<\/jats:italic> (<jats:italic>n<\/jats:italic>\u00a0=\u00a07), <jats:italic>Candida glabrata<\/jats:italic> (<jats:italic>n<\/jats:italic>\u00a0=\u00a01) and <jats:italic>Trichosporon<\/jats:italic> (<jats:italic>n<\/jats:italic>\u00a0=\u00a02). In the minimum inhibitory concentration (MIC) study, the mean \u00b1 standard error of the mean (SEM) MICs of the antifungals for <jats:italic>T. rubrum<\/jats:italic> were as follows: terbinafine 0.01 \u00b1 0.003, oxiconazole 0.16 \u00b1 0.05, sulkonazole 0.31 \u00b1 0.05, miconazole 0.45 \u00b1 0.15, itraconazole 0.74 \u00b1 0.01, ketokonazole 1.03 \u00b1 0.17, ciclopiroxolamine 1.30 \u00b1 0.12, bifonazole 1.94 \u00b1 0.51, griseofulvin 4.87 \u00b1 0.61, and fluconazole 17.91 \u00b1 3.67\u00a0\u00b5g\/mL.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Our study supports that azoles could be used as first\u2010line treatment, as oxiconazole is very effective for both dermatophytes and <jats:italic>C. albicans<\/jats:italic>. Correlation between <jats:italic>in vitro<\/jats:italic> results and clinical outcomes of cases of dermatophytes is still to be established and interpretive breakpoints defined, in order to increase the quality of patient care in tinea pedis.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2006.01396.x","type":"journal-article","created":{"date-parts":[[2006,1,27]],"date-time":"2006-01-27T12:39:04Z","timestamp":1138365544000},"page":"158-165","source":"Crossref","is-referenced-by-count":8,"title":["What defines the quality of patient care in tinea pedis?"],"prefix":"10.1111","volume":"20","author":[{"given":"S","family":"Mistik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Ferahbas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AN","family":"Koc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Ayangil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Ozturk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1,4]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"crossref","unstructured":"Bell\u2010SyerSE HartR CrawfordFet al.Oral treatments for fungal infections of the skin of the foot.Cochrane Database Syst Rev2002: CD003584.","DOI":"10.1002\/14651858.CD003584"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-0960.1999.00360.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.1999.tb00908.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1993.tb03510.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1476-7961-2-5"},{"key":"e_1_2_6_7_2","first-page":"2095","article-title":"Topical treatment of common superficial tinea infections","volume":"65","author":"Weinstein A","year":"2002","journal-title":"Am Fam Physician"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.1999.tb00909.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.110378"},{"key":"e_1_2_6_10_2","first-page":"101","article-title":"Dermatophyte infections","volume":"67","author":"Hainer BL","year":"2003","journal-title":"Am Fam Physician"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(02)00065-X"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-97931-6"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2003.10.003"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.9.2524-2528.2001"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.107754"},{"key":"e_1_2_6_16_2","first-page":"1275","volume-title":"Manual of Clinical Microbiology","author":"Kane J","year":"1999"},{"key":"e_1_2_6_17_2","unstructured":"LaroneDH.Medically Important Fungi: A Guide to Identification 2nd edn.ASM Press Washington DC 1993."},{"key":"e_1_2_6_18_2","first-page":"689","volume-title":"Bailey and Scott's Diagnostic Microbiology","author":"Glenn DR","year":"1994"},{"key":"e_1_2_6_19_2","first-page":"6.10","volume-title":"Clinical Microbiology Procedures Handbook","author":"Espinel\u2010Ingroff A","year":"1992"},{"key":"e_1_2_6_20_2","first-page":"1135","volume-title":"Zinsser Microbiology","author":"Mitchell TG","year":"1992"},{"key":"e_1_2_6_21_2","unstructured":"National Committee for Clinical Laboratory Standards.Reference method for broth dilution antifungal susceptibility testing of yeast; approved standard. 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