{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T01:18:23Z","timestamp":1771550303603,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,4,21]],"date-time":"2006-04-21T00:00:00Z","timestamp":1145577600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2006,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Narrow band ultraviolet B (NB\u2010UVB) phototherapy has been used successfully for the treatment of vitiligo. Recently, topical calcipotriol has also been claimed to be effective, either as monotherapy or as a part of combination therapies.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> The aim of the present study was to compare the clinical efficacy of NB\u2010UVB and NB\u2010UVB plus topical calcipotriol in the treatment of vitiligo.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> NB\u2010UVB treatment was given to 24 patients with generalized vitiligo three times weekly. Topical calcipotriol cream was only applied to the lesions located on the right side of the body. Treatment was continued for 6\u00a0months. Treatment efficacy was evaluated by determining the average response rates of the lesions at 3\u2010month intervals.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> The average response rates of patients receiving combination of NB\u2010UVB plus calcipotriol and NB\u2010UVB alone were 51\u00a0\u00b1\u00a019.6% and 39\u00a0\u00b1\u00a018.9%, respectively. The median cumulative UVB dose and number of UVB exposures for initial repigmentation were 6345 mj\/cm<jats:sup>2<\/jats:sup> (range; 2930\u201330980) and 18 (range; 12\u201367) for the combination therapy, and 8867.5 mj\/cm<jats:sup>2<\/jats:sup> (range; 2500\u201330980) and 24 (range; 15\u201367) for the narrow band UVB therapy, respectively.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> These findings indicate that concurrent topical calcipotriol potentates the efficacy of NB\u2010UVB in the treatment of vitiligo. This combination not only provides earlier pigmentation with lower total UVB dosage and less adverse UVB effects, but also reduces the duration and cost of treatment as well.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2006.01546.x","type":"journal-article","created":{"date-parts":[[2006,4,21]],"date-time":"2006-04-21T17:08:01Z","timestamp":1145639281000},"page":"553-557","source":"Crossref","is-referenced-by-count":50,"title":["Combination of narrow band UVB and topical calcipotriol for the treatment of vitiligo"],"prefix":"10.1111","volume":"20","author":[{"given":"EO","family":"Goktas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Aydin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Senturk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MT","family":"Canturk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AY","family":"Turanli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,4,21]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70194-X"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2000.00709.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.3.393"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2002.01486_3.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0781.2003.00039.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(05)70021-8"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.114752"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1997.03890480045006"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000017991"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.112357"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2001.04286.x"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2001.04381.x"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb03373.x"},{"key":"e_1_2_5_15_2","first-page":"72","article-title":"The future of vitamin D in dermatology","volume":"37","author":"Kragballe K","year":"1997","journal-title":"J Am Acad Dermatol"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2002.00407.x"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2003.00795.x"},{"key":"e_1_2_5_18_2","doi-asserted-by":"crossref","unstructured":"HartmannA LurzC HammHet al.Narrow\u2010band UVB311\u00a0nm vs. Broad\u2010band UVB therapy in combination with topical calcipotriol vs. placebo in vitiligo.Int J Dermatol2005;44:736\u2013742.","DOI":"10.1111\/j.1365-4632.2004.02154.x"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2006.01546.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2006.01546.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T16:39:00Z","timestamp":1697042340000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2006.01546.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4,21]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["10.1111\/j.1468-3083.2006.01546.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2006.01546.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4,21]]}}}