{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T04:32:58Z","timestamp":1781065978201,"version":"3.54.1"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,4,21]],"date-time":"2006-04-21T00:00:00Z","timestamp":1145577600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2006,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Several options for treatment of early mycosis fungoides (MF) offer similar success rates. Previous small studies have shown UVB to be at least as effective as PUVA.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> To summarize our experience with UVB treatment of early MF.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> A retrospective analysis of early\u2010stage MF patients treated by narrow band (NB) or broad band (BB) UVB in our institution between 1996 and 2002. Most patients achieving complete response (CR) were put on maintenance until natural sun exposure was possible and followed up every 3\u20136\u00a0months. The results were compared to those previously reported regarding PUVA.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Sixty\u2010eight and 43 patients were treated by NB and BB UVB, respectively. Eighty\u2010six per\u00a0cent (84 and 89% in NB and BB UVB groups, respectively) of IA and 71% (78 and 44% in NB and BB UVB groups, respectively) of IB patients achieved CR within a mean of 12.8 and 10.6\u00a0weeks, respectively. When maintenance was stopped, 65 and 30% had not relapsed after an average follow up of 27 and 222\u00a0weeks, respectively. Non\u2010relapse rate was 33 and 48% for those having had vs. those not having had maintenance, respectively.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Our results are comparable to all previously reported for skin\u2010targeted treatments, including PUVA and, to our belief, reflect the nature of early MF, in which CR can probably be achieved in most of the patients. Among the responding patients there is no relapse during prolonged follow\u2010up in about one third of the cases. Thus, we believe treatment should be stopped completely following first CR induction and maintenance treatment should be considered for relapsing patients only. Both broad and narrow UVB options are good and future choices should be made on the basis of short\u2010 and long\u2010term side\u2010effects.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2006.01557.x","type":"journal-article","created":{"date-parts":[[2006,4,21]],"date-time":"2006-04-21T17:08:01Z","timestamp":1145639281000},"page":"565-572","source":"Crossref","is-referenced-by-count":49,"title":["UVB in the management of early stage mycosis fungoides"],"prefix":"10.1111","volume":"20","author":[{"given":"F","family":"Pavlotsky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Barzilai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Kasem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Shpiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Trau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,4,21]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"725","article-title":"Report of the committee on staging and classification of cutaneous T\u2010cell lymphoma","volume":"68","author":"Bunn PA","year":"1979","journal-title":"Cancer Treat Rep"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.117722"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.7.857"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.135.1.26"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1396-0296.2003.01639.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1396-0296.2003.01641.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.2.165"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1396-0296.2003.01647.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197608)38:2<683::AID-CNCR2820380210>3.0.CO;2-V"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1977.01640080049003"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(80)92937-2"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(84)70030-2"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)61492-X"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)90241-4"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.80"},{"key":"e_1_2_6_17_2","first-page":"55","article-title":"Treatment of mycosis fungoides with PUVA","volume":"4","author":"Honigsmann H","year":"1987","journal-title":"Photodermatology"},{"key":"e_1_2_6_18_2","doi-asserted-by":"crossref","first-page":"475","DOI":"10.2340\/0001555576475478","article-title":"PUVA in early mycosis fungoides may give long term remission and delay extracutaneous spread","volume":"76","author":"Roupe G","year":"1996","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.110896"},{"key":"e_1_2_6_20_2","first-page":"450","article-title":"Mycosis Fungoides. 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