{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:18:04Z","timestamp":1761707884697},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2006,4,21]],"date-time":"2006-04-21T00:00:00Z","timestamp":1145577600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Genital diseases include a wide range of lesions e.g. infectious and inflammatory. In most cases a clinical diagnosis is reached without the need for a biopsy. Nonetheless, a genital biopsy is safe and may help to confirm the diagnosis. We established a dedicated diagnostic biopsy clinic in 2003. Our objective was to evaluate the effectiveness of our diagnostic biopsy clinic and compare it with other Genitourinary medicine (GUM) clinics in the UK. A retrospective case\u2010note study was performed on 71 patients referred to the biopsy clinic with persistent genital lesions over a 12\u2010month period. Forty\u2010seven biopsies were performed (71% biopsy rate). 43 specimens (92%) were appropriate for histopathological diagnosis. Of these 15% were lichen planus, 15% lichen sclerosis, 10% psoriasis, 7.5% each: eczema, Zoon's and non\u2010specific balanitis. The remainder represented a variety of other conditions. In 27 cases (68%) the clinical diagnosis was consistent with the histological result.<\/jats:p><jats:p>The possibility of self\u2010referral and walk\u2010in nature of our GUM service substantially decrease the waiting times for assessment of anogenital disorders. We had a lower biopsy rate for the diagnosis of non\u2010specific balanitis (7.5%) compared with the average rate (21.5%) in 14 UK GUM clinics and good agreement between clinical and histological diagnosis. An empirical first treatment, with simple emollients before biopsy, appears to be a safe clinical approach for the treatment of non\u2010specific balanitis. A multidisciplinary approach (GUM physicians, dermatologists and urologists\/gynaecologists) could help prevent unnecessary biopsies and improve correlation between clinical and histological diagnosis.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2006.01563.x","type":"journal-article","created":{"date-parts":[[2006,4,21]],"date-time":"2006-04-21T17:08:01Z","timestamp":1145639281000},"page":"905-910","source":"Crossref","is-referenced-by-count":8,"title":["The usefulness of a diagnostic biopsy clinic in a genitourinary medicine setting: recent experience and a review of the literature"],"prefix":"10.1111","volume":"20","author":[{"given":"I","family":"Palamaras","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Hamill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Sethi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Wilkinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Lamba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,4,21]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"407","article-title":"Value of performing biopsies in genitourinary clinics","volume":"66","author":"Arumainayagam JT","year":"1990","journal-title":"Genitourinary Med"},{"key":"e_1_2_7_3_2","first-page":"400","article-title":"Clinical features and management of recurrent balanitis; association with atopy and genital washing","volume":"69","author":"Birley HD","year":"1993","journal-title":"Genitourinary Med"},{"key":"e_1_2_7_4_2","first-page":"166","article-title":"Penile dermatoses: a clinical and histopathological study","volume":"68","author":"Hillman RJ","year":"1992","journal-title":"Genitourinary Med"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1258\/095646202760159729"},{"key":"e_1_2_7_6_2","first-page":"421","article-title":"Biopsy of male genital dermatosis","volume":"73","author":"Mallon E","year":"1997","journal-title":"Genitourinary Med"},{"key":"e_1_2_7_7_2","first-page":"S85","article-title":"National guideline for the management of balanitis.","volume":"75","author":"Clinical Effectiveness Group.","year":"1999","journal-title":"Sex Transm Infect"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.05012.x"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1995.tb00718.x"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1994.tb01624.x"},{"key":"e_1_2_7_11_2","first-page":"1","article-title":"Genital viral infections. 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