{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T22:36:30Z","timestamp":1713479790305},"reference-count":18,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2006,8,3]],"date-time":"2006-08-03T00:00:00Z","timestamp":1154563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> The incidence of malignant melanoma of the skin has risen in every part of the world where reliable cancer registration data are found.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> Our study aims to describe the changing incidence of and survival from invasive cutaneous malignant melanoma in Malta, by analysing the data from the 211 cases that were registered at the Malta National Cancer Registry between 1993 and 2002.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> The age standardized incidence rates for invasive cutaneous malignant melanoma rose from 3.7 per 100\u00a0000 population per year for males and 5.1 for females in the first 5\u2010year period, to 8.0 per 100\u00a0000 population per year for males and 5.9 for females in the second 5\u2010year period. In both sexes, numbers of thin (\u2264\u00a01.0\u00a0mm) invasive melanomas increased significantly between 1993 and 2002; males also registered a significant increase in intermediate\u2010thickness (1.01\u20134.0\u00a0mm) melanomas. The increase in numbers of thin and intermediate\u2010thickness melanomas between the two 5\u2010year periods was greatest in patients aged 60\u00a0years and over. The overall absolute 5\u2010year survival rate for the first period was 74% and for the second period 92%.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Numbers of reported cases of invasive cutaneous malignant melanoma in Malta have more than doubled during the 10\u2010year study period. This is mostly due to a marked rise in the diagnosis of thin melanomas in both sexes, occurring mainly in patients aged 60\u00a0years and over. As thin melanomas are of low metastasizing potential, this has resulted in an increase in survival between the two 5\u2010year study periods.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2006.01694.x","type":"journal-article","created":{"date-parts":[[2006,8,3]],"date-time":"2006-08-03T13:51:34Z","timestamp":1154613094000},"page":"958-963","source":"Crossref","is-referenced-by-count":4,"title":["A profile of invasive cutaneous malignant melanoma in Malta: 1993\u20132002"],"prefix":"10.1111","volume":"20","author":[{"given":"S","family":"Aquilina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Dalmas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Calleja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Gatt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Scerri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,8,3]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(02)00037-2"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2004.06.003"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70562-1"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7116.1117"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008390-199902000-00013"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.02710.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06071.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdg754"},{"key":"e_1_2_6_10_2","first-page":"1282","volume-title":"Cancer Epidemiology and Prevention","author":"Armstrong BK","year":"1996"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19980812)77:4<533::AID-IJC10>3.0.CO;2-7"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2002.00376.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008390-199404000-00005"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05599.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.312.7024.137"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7116.1106"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910470402"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1995.307"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.135.3.275"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2006.01694.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2006.01694.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T16:55:21Z","timestamp":1697043321000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2006.01694.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8,3]]},"references-count":18,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["10.1111\/j.1468-3083.2006.01694.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2006.01694.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,8,3]]}}}