{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T22:38:37Z","timestamp":1777329517380,"version":"3.51.4"},"reference-count":13,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2006,8,31]],"date-time":"2006-08-31T00:00:00Z","timestamp":1156982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> It is not known why some individuals infected with herpes simplex virus type 2 (HSV\u20102), experience frequent recurrences, while most of those infected have a completely silent infection.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> We wanted to study if local factors in the skin could explain this difference.<\/jats:p><jats:p><jats:bold>Design\u2002<\/jats:bold> 21 HSV\u20102 seropositive patients, 10 with history of &gt;8 clinical recurrences a year (symptomatics) and 11 without symptoms of genital herpes (asymptomatics) were included. All had to answer a questionnaire. With standardised methods, the skin temperature, pH, and the skin barrier function, expressed as transepidermal water loss (TEWL) and skin capacitance, were measured on labium majus and perineum. Culture for bacteria was performed from the same regions.<\/jats:p><jats:p><jats:bold>Results and Conclusion \u2002<\/jats:bold> No significant differences in terms of pH and skin barrier function were registered between symptomatic and asymptomatic patients. Asymptomatic patients had a tendency (0.06) to a higher colonisation with lactobacilli on labium majus than symptomatic patients.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2006.01729.x","type":"journal-article","created":{"date-parts":[[2006,8,31]],"date-time":"2006-08-31T15:31:22Z","timestamp":1157038282000},"page":"1086-1089","source":"Crossref","is-referenced-by-count":6,"title":["The microenvironment of vulvar skin in women with symptomatic and asymptomatic herpes simplex virus type 2 (HSV\u20102) infection"],"prefix":"10.1111","volume":"20","author":[{"given":"G\u2010B","family":"L\u00f6whagen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Bonde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U","family":"Forsgren\u2010Brusk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Runeman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Tunb\u00e4ck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,8,31]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/174.3.470"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199509213331205"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/314729"},{"key":"e_1_2_6_5_2","doi-asserted-by":"crossref","first-page":"3088","DOI":"10.1128\/jcm.32.12.3088-3090.1994","article-title":"Correlation between detection of herpes simplex virus in oral secretions by PCR and susceptibility to experimental UV radiation\u2010induced herpes labialis","volume":"32","author":"Kriesel JD","year":"1994","journal-title":"J Clin Microbiol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015550410024562"},{"key":"e_1_2_6_7_2","first-page":"277","article-title":"The vulvar skin microenvironment: influence of different panty liners on temperature, pH and microflora","volume":"84","author":"Runeman B","year":"2004","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015550310007409"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1990.tb00078.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1995.tb02069.x"},{"key":"e_1_2_6_11_2","first-page":"9","article-title":"Dry skin in atopic dermatitis","volume":"177","author":"Linde YW","year":"1992","journal-title":"Acta Derm Venereol Suppl"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2003.07.001"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1086\/429622"},{"key":"e_1_2_6_14_2","first-page":"665","article-title":"Review. Laboratory detection of group B Streptococcus for prevention of perinatal disease","volume":"23","author":"Picard FJ","year":"2004","journal-title":"Eur J Vlin Microbiol Infect Dis"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2006.01729.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2006.01729.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T18:14:16Z","timestamp":1697048056000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2006.01729.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8,31]]},"references-count":13,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["10.1111\/j.1468-3083.2006.01729.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2006.01729.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,8,31]]}}}