{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T01:40:28Z","timestamp":1773798028982,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2006,10,11]],"date-time":"2006-10-11T00:00:00Z","timestamp":1160524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Herpes simplex virus (HSV) infections are among the most common infectious diseases in humans. The prevalence of herpes simplex viruses type 1 (HSV\u20101) and type 2 (HSV\u20102) varies widely across the world. HSV\u20102 infection is the primary cause of genital herpes. It is highly prevalent in human populations in many parts of the world, and is the most common cause of genital ulcer disease worldwide. In spite of the large prevalence and growing incidence of herpes simplex infection (HSV\u20101 and HSV\u20102), relatively few data have been published regarding the seroprevalence of herpes simplex infection, while no data exist regarding the Turkish population.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> We aimed to investigate the prevalence of HSV\u20101 and HSV\u20102 in selected populations in Turkey. A cross\u2010sectional study was conducted involving 2082 serum samples of 725 adults, 300 pregnant women, 200 blood donors, 483 sex workers and 110 patients with genital warts and 264 hotel staff in Istanbul, Turkey. All serum samples were assessed for HSV1 and HSV\u20102 IgG antibodies using an HSV\u2010type specific, enzyme\u2010linked immunosorbent assay (ELISA).<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> The prevalence of HSV\u20102 and HSV\u20101 antibodies was 4.8 and 85.3% in sexually active adults; 5.5 and 96% in blood donors; 5 and 98% in pregnant women, 17.3 and 93.6% in patients with genital warts; 8.3 and 97.3% in hotel staff; and 60% and 99% in sex workers.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> These results confirm a higher prevalence of HSV infection than estimated, especially in high risk groups in Turkey. The high prevalence of HSV infection underlines the need for education among these populations.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2006.01766.x","type":"journal-article","created":{"date-parts":[[2006,10,11]],"date-time":"2006-10-11T09:26:05Z","timestamp":1160558765000},"page":"1232-1236","source":"Crossref","is-referenced-by-count":19,"title":["Seroprevalence of herpes simplex virus type 1 and type 2 in Turkey"],"prefix":"10.1111","volume":"20","author":[{"given":"N","family":"Dolar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Serdaroglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Ergin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,16]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(01)00003-1"},{"key":"e_1_2_5_3_2","first-page":"19","article-title":"Seroepidemiological and sociological patterns of herpes simplex virus infection in the world","volume":"69","author":"Nahmias AJ","year":"1990","journal-title":"Scand J Infect Dis"},{"key":"e_1_2_5_4_2","first-page":"285","volume-title":"Sexually Transmitted Diseases","author":"Corey L","year":"1999"},{"key":"e_1_2_5_5_2","first-page":"2","article-title":"Epidemiology of genital herpes simplex virus infection in developed countries","volume":"11","author":"Malkin JE","year":"2004","journal-title":"Herpes"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(05)70049-8"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/30.3.580"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/165.2.251"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03720070048033"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/158.1.109"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199102143240704"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00457-2"},{"key":"e_1_2_5_13_2","first-page":"1138","article-title":"Neonatal herpes simplex virus infections","volume":"65","author":"Rudnick CM","year":"2002","journal-title":"Am Fam Physician"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-4-10"},{"key":"e_1_2_5_15_2","first-page":"106","article-title":"Asymptomatic herpes simplex virus type 2 (HSV\u20102) infection among pregnant women in Turkey","volume":"120","author":"Duran N","year":"2004","journal-title":"Indian J Med Res"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.2.407-413.2002"},{"key":"e_1_2_5_17_2","first-page":"1291","volume-title":"Manual of Clinical Microbiology","author":"Jerome KR"},{"key":"e_1_2_5_18_2","first-page":"359","article-title":"Performance of two commercial enzyme\u2010linked immunosorbent assay kits using recombinant glycoprotein G2 antigen for detection of herpes simplex virus type 2 specific antibodies","volume":"12","author":"Reddy SM","year":"2005","journal-title":"Clin Diagn Laboratory Immunol"},{"key":"e_1_2_5_19_2","first-page":"216","volume-title":"Clinical Microbiology and Infection","author":"Aks\u00f6zek A","year":"2004"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2003.005850"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1086\/343739"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.78.3.201"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9071(200006)61:2<201::AID-JMV5>3.0.CO;2-P"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1086\/344317"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-200107000-00011"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.1.84-89.2003"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/27.1.127"},{"key":"e_1_2_5_28_2","unstructured":"B\u00fcnzliD WietlisbachV JeanninA.Epidemiology of herpes simplex virus type 1 and 2 in Switzerland: a population\u2010based study.42nd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy.San Diego California 2002; 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