{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:49:05Z","timestamp":1760042945509},"reference-count":14,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2006,9,29]],"date-time":"2006-09-29T00:00:00Z","timestamp":1159488000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Pulsed dye laser (PDL) treatment is widely used for poikiloderma of Civatte. Some adverse events in small numbers of patients have been reported. Guidelines for treatment of poikiloderma of Civatte do not exist.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> To report the occurrence of persistent depigmentation as a late adverse event in a series of patients with poikiloderma of Civatte after treatment with PDL.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Eight patients (seven women and one man, mean age 48\u00a0years) with poikiloderma of Civatte were treated with PDL using a 585\u2010nm wavelength and a fixed pulse duration of 450\u00a0\u00b5s. In all patients one or two test PDL patches were performed and reviewed after 3\u00a0months. All of the patients tolerated the testing without complications. Subsequent treatments were undertaken at intervals of 3\u00a0months.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> All patients were treated with fluences between 3.5 and 7\u00a0J\/cm<jats:sup>2<\/jats:sup>, using a 7\u2010 or 10\u2010mm spot size. All patients had a good result with respect to clearing of the vascular component. Nevertheless, six of them, treated with 5\u20137\u00a0J\/cm<jats:sup>2<\/jats:sup>, reported severe depigmentation 4\u201311\u00a0months after treatment. Two patients treated with lower fluences (3.5\u20135.5\u00a0J\/cm<jats:sup>2<\/jats:sup>) did not report this depigmentation.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Great care is needed when PDL treatment is used for poikiloderma of Civatte. Pigment changes have been incidentally mentioned as late complications but have not been well documented as the late depigmentation has been in this series. It is advisable to use fluences as low as possible, and not exceeding an upper limit of 5\u00a0J\/cm<jats:sup>2<\/jats:sup>, on a 10\u2010mm spot size. More research is needed to define an optimal pulse duration.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2006.01782.x","type":"journal-article","created":{"date-parts":[[2006,9,29]],"date-time":"2006-09-29T13:33:35Z","timestamp":1159536815000},"page":"1248-1251","source":"Crossref","is-referenced-by-count":30,"title":["Treatment of poikiloderma of Civatte with the pulsed dye laser: a series of patients with severe depigmentation"],"prefix":"10.1111","volume":"20","author":[{"given":"MM","family":"Meijs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"FAA","family":"Blok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MA","family":"De Rie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,16]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(87)70187-X"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2005.01213.x"},{"key":"e_1_2_5_4_2","first-page":"40","article-title":"Benign skin changes associated with chronic sunlight exposure","volume":"34","author":"Goldberg LH","year":"1984","journal-title":"Cutis"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2000.00060.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1972.tb01753.x"},{"key":"e_1_2_5_7_2","first-page":"19","volume-title":"Cutaneous Laser Surgery.","author":"Goldman MP","year":"1994"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.126.4.547b"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1080\/14628839950517093"},{"key":"e_1_2_5_10_2","first-page":"1191","article-title":"Treatment of poikiloderma of Civatte with the potassium titanyl phosphate (KTP) laser","volume":"140","author":"Batta K","year":"1999","journal-title":"Br J Dermatol"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70413-5"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(05)70448-4"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1990.tb00002.x"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)90346-1"},{"key":"e_1_2_5_15_2","first-page":"125","article-title":"Correspondence","volume":"1","author":"Langeland J","year":"1999","journal-title":"J Cutan Laser Ther"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2006.01782.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2006.01782.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T09:08:32Z","timestamp":1697015312000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2006.01782.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,16]]},"references-count":14,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["10.1111\/j.1468-3083.2006.01782.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2006.01782.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,16]]}}}