{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T06:03:46Z","timestamp":1777356226551,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,1,29]],"date-time":"2007-01-29T00:00:00Z","timestamp":1170028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002\u2002<\/jats:bold> A large variety of therapeutic agents are being used for the treatment of vitiligo, but treatment remains a challenge. Recently, monochromatic phototherapies such as 311\u2010nm narrowband ultraviolet B therapy and 308\u2010nm xenon chloride excimer laser have been reported to be an effective and safe therapeutic option in children and adult patients with vitiligo. Single reports stipulate that the addition of topically applied calcipotriol to phototherapy increases its effectiveness.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> The purpose of the present pilot study was to determine if the addition of topical calcipotriol increases the efficacy of the 308\u2010nm xenon chloride excimer in the treatment of vitiligo.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Ten patients with vitiligo with essentially bilateral symmetrical lesions were enrolled in this prospective right\/left comparative, single\u2010blinded trial conducted over a 15\u2010month period. All patients received 308\u2010nm XeCl excimer laser therapy three times weekly. Calcipotriol ointment (Daivonex\u00ae) was applied to lesions on one side of the body twice daily.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> After 24 treatments (8\u00a0weeks), nine patients were evaluated. Eight patients showed evidence of repigmentation on both body sides, with no significant difference between the body side treated with calcipotriol and excimer laser and the side treated with excimer laser alone. The mean repigmentation rate was 22.4% (1\u2013 37%).<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> The addition of calcipotriol ointment to 308\u2010nm xenon chloride excimer laser phototherapy does not significantly enhance its efficacy. Small additive effects must be investigated in a larger trial.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2006.02016.x","type":"journal-article","created":{"date-parts":[[2007,1,29]],"date-time":"2007-01-29T09:11:08Z","timestamp":1170061868000},"page":"504-508","source":"Crossref","is-referenced-by-count":58,"title":["Combination of 308\u2010nm xenon chloride excimer laser and topical calcipotriol in vitiligo"],"prefix":"10.1111","volume":"21","author":[{"given":"SM","family":"Goldinger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Dummer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Schmid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Burg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Seifert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"L\u00e4uchli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,3,5]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200464010-00006"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.114752"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2003.00795.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1997.03890480045006"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90133-6"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.121357"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2003.01997.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02154.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12462151"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.1999.00083.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2004.00114.x"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2004.tb00674.x"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2001.00220.x"},{"key":"e_1_2_5_15_2","volume-title":"Dermatology.","author":"Bolognia J","year":"2003"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.188.6.1203"},{"key":"e_1_2_5_17_2","doi-asserted-by":"crossref","unstructured":"LuccheseA WillersJ MittelmanA KanducD DummerR.Proteomic scan for tyrosinase peptide antigenic pattern in vitiligo and melanoma: role of sequence similarity and HLA\u2010DR1 affinity.J Immunol2005;175:7009\u20137020.","DOI":"10.4049\/jimmunol.175.10.7009"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2005.23760.x"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2002.00407.x"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1159\/000017991"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.12.1656"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.9.1065"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2004.30058.x"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2006.02016.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2006.02016.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T23:38:02Z","timestamp":1696981082000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2006.02016.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3,5]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["10.1111\/j.1468-3083.2006.02016.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2006.02016.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,3,5]]}}}