{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T11:38:11Z","timestamp":1788781091748,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,10,18]],"date-time":"2007-10-18T00:00:00Z","timestamp":1192665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Non\u2010healing leg ulcers represent a treatment problem.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> Investigate grafting of autologous suction blister roofs as treatment.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Twenty\u2010nine chronic, non\u2010healing leg ulcers of various aetiologies in 18 inpatients were treated by autologous epidermal grafting using the roofs of suction blisters.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> 55% of ulcers completely healed 2 to 6 weeks after grafting. A 50\u201390% reduction in size was documented in 34% and no change was observed in 11% of ulcers. Twelve weeks after grafting, 89% of ulcers were healed completely. In most ulcers, we observed a stimulation of reepithelialization from the wound edge (\u2018edge effect\u2019) and an accelerated formation of healthy granulation tissue. During a follow\u2010up period of 12 months, 90% of the ulcers remained healed.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Grafting of autologous suction blister roofs is an effective treatment option for non\u2010healing leg ulcers. The advantages of the method are its lack of pain, low costs and immediate availability.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2007.02148.x","type":"journal-article","created":{"date-parts":[[2007,10,18]],"date-time":"2007-10-18T12:01:15Z","timestamp":1192708875000},"page":"7-10","source":"Crossref","is-referenced-by-count":22,"title":["Autologous suction blister grafting for chronic leg ulcers"],"prefix":"10.1111","volume":"22","author":[{"given":"U","family":"Costanzo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Streit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LR","family":"Braathen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,12,20]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"1","article-title":"Medical costs of treating venous stasis ulcers: evidence from a retrospective cohort study","volume":"4","author":"Olin JW","year":"1999","journal-title":"Vasc Med"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(86)70048-0"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1987.tb07491.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.3.293"},{"key":"e_1_2_5_6_2","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2340\/000155555207209","article-title":"Suction blister transplantation for leg ulcers","volume":"55","author":"Hentzer B","year":"1975","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.135.8.991-a"},{"key":"e_1_2_5_8_2","first-page":"229","volume-title":"Bioengineering of the Skin: Skin Surface Image and Analysis","author":"Bahmer FA.","year":"1997"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1968.15"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1971.04000240016002"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1988.01670110016003"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1991.tb00595.x"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1986.tb00526.x"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1993.tb02240.x"},{"key":"e_1_2_5_15_2","first-page":"170","article-title":"Treatment of leg ulcers with cultured epithelial autografts: treatment protocol and five year experience","volume":"7","author":"Limova M","year":"1995","journal-title":"Wounds"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2000.00347.x"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/328817a0"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1991.tb06062.x"},{"key":"e_1_2_5_19_2","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1001\/archderm.1993.01680250093014","article-title":"The biology of skin grafts","volume":"29","author":"Kirsner RS","year":"1993","journal-title":"Arch Dermatolog"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12298415"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2007.02148.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2007.02148.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T06:31:23Z","timestamp":1697005883000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2007.02148.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12,20]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["10.1111\/j.1468-3083.2007.02148.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2007.02148.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,12,20]]}}}