{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:58:50Z","timestamp":1787014730150,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T00:00:00Z","timestamp":1204848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Background\u2002<\/jats:bold>\n                    This study aims to study the clinical and histopathological characteristics of hypocomplementemic and normocomplementemic urticarial vasculitis (HUVS and NUV) among dermatology clinic attendees in a tertiary care hospital in South India.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Patients and methods\u2002<\/jats:bold>\n                    A prospective study was conducted in the dermatology department from February 2003 to May 2004.\n                  <\/jats:p>\n                  <jats:p>Seventy\u2010five patients met the inclusion criteria for UV. Sixty\u2010eight patients in whom complement levels were available were classified into either NUV or HUVS groups. Clinical features, laboratory parameters and histological features were compared, and the significance of differences was established using Pearson's Chi\u2010squared test.<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results\u2002<\/jats:bold>\n                    There was a female preponderance among patients with HUVS. Wheals\u00a0&gt;\u00a024\u00a0h were seen in 90% of patients, and in 54.4% of patients, the wheals were partially blanching or non\u2010blanching. Angioedema was more prevalent in patients with NUV than HUVS (44.4% vs. 21.4%). Systemic involvement was seen in 64.3% of patients with HUVS and 44.4% of patients with NUV. Fever, ANA positivity and systemic lupus erythematosus (SLE) were significantly associated with HUVS. In most cases of UV, a provoking factor could not be identified. Neutrophilic small vessel vasculitis was seen in 42.9% of patients with HUVS and 16.6% patients with NUV. Direct immunofluorescence test showing immunoreactants at the dermo\u2010epidermal junction were present in 60% of patients with HUVS and 33.3% patients with NUV.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion\u2002<\/jats:bold>\n                    The clinical features of Indian patients with UV were similar to those reported from the West. Fever, ANA positivity and SLE were significantly associated with HUVS.\n                  <\/jats:p>","DOI":"10.1111\/j.1468-3083.2007.02641.x","type":"journal-article","created":{"date-parts":[[2008,3,7]],"date-time":"2008-03-07T11:35:20Z","timestamp":1204889720000},"page":"789-794","source":"Crossref","is-referenced-by-count":48,"title":["Clinicopathologic profile of normocomplementemic and hypocomplementemic urticarial vasculitis: a study from South India"],"prefix":"10.1111","volume":"22","author":[{"given":"CVP","family":"Dincy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"George","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Jacob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Mathai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Pulimood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EP","family":"Eapen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,5,6]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"340","article-title":"Hypocomplementemia with cutaneous vasculitis and arthritis: possible immune complex syndrome","volume":"48","author":"McDuffie FC","year":"1973","journal-title":"Mayo Clin Proc"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197706232962505"},{"key":"e_1_2_5_4_2","first-page":"979","volume-title":"Lever's Histopathology of the Skin","author":"Elder DE","year":"2005"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(80)90216-8"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1982.tb00295.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199501000-00003"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(92)70069-R"},{"key":"e_1_2_5_9_2","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/S0190-9622(24)00193-2","article-title":"Clinicopathologic correlation of hypocomplementemic and normocomplementemic urticarial vasculitis","volume":"38","author":"Davis MDP","year":"1998","journal-title":"J Am Acad Dermatol"},{"key":"e_1_2_5_10_2","first-page":"724","article-title":"Geha RS, KF; Skin lesions, angioedema, eosinophilia and hypocomplementaemia","volume":"89","year":"1975","journal-title":"J Pediatr"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(90)90503-6"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1988.tb00921.x"},{"key":"e_1_2_5_13_2","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1001\/jama.1976.03270190021021","article-title":"Vasculitis with urticaria, hypocomplementemia, and multiple system involvement","volume":"236","author":"Feig PU","year":"1976","journal-title":"JAMA"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(82)70139-2"},{"key":"e_1_2_5_15_2","first-page":"536","article-title":"Hypocomplementemic urticarial vasculitis and lower cranial nerve palsies","volume":"48","author":"Koul PA","year":"2000","journal-title":"J Assoc Phys India"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1986.tb00490.x"},{"key":"e_1_2_5_17_2","first-page":"232","volume-title":"Skin Pathology","author":"Weedon D.","year":"2002"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2007.02641.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2007.02641.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T03:37:35Z","timestamp":1708659455000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2007.02641.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,6]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["10.1111\/j.1468-3083.2007.02641.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2007.02641.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5,6]]}}}