{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,20]],"date-time":"2025-04-20T16:41:12Z","timestamp":1745167272126},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2008,8,18]],"date-time":"2008-08-18T00:00:00Z","timestamp":1219017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Anti\u2010tumour necrosis factors (anti\u2010TNF) are more and more used, but the rate of skin adverse events is not known.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> The aim was to assess the number of skin infections and other dermatoses in patients treated with anti\u2010TNF\u03b1.<\/jats:p><jats:p><jats:bold>Patients and methods\u2002<\/jats:bold> One hundred eighty\u2010seven patients suffering from rheumatoid arthritis or ankylosing spondylitis underwent a dermatological exam. Patients with anti\u2010TNF were compared with those without this treatment in a prospective transversal study.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Among them, 59 patients were treated with anti\u2010TNF\u03b1 and steroids were prescribed in 100 cases. There was no difference in the prevalence of skin infections or eczema or tumours. Skin drug reactions were observed in six patients. Infections by dermatophytes appear very frequent, approaching 70% in both groups.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> This study shows that skin infections (or other skin diseases) are not more frequent in these patients. No differences were observed in infections (bacterial fungal, parasital or viral), tumours, psoriasis or the manifestations of atopic dermatitis. Nonetheless, a long\u2010term survey might be interesting, especially about skin tumours.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2008.02935.x","type":"journal-article","created":{"date-parts":[[2008,8,18]],"date-time":"2008-08-18T14:57:20Z","timestamp":1219071440000},"page":"1471-1477","source":"Crossref","is-referenced-by-count":17,"title":["Cutaneous events during treatment of chronic inflammatory joint disorders with anti\u2010tumour necrosis factor alpha: a cross\u2010sectional study"],"prefix":"10.1111","volume":"22","author":[{"given":"AC","family":"Davaine","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Saraux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Prigent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Kupfer\u2010Bessaguet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Roswag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Plantin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Schoenlaub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Talarmin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Zagnoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Misery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,11,24]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/ar1724"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/383317"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.10524"},{"key":"e_1_2_6_5_2","first-page":"1900","article-title":"Development, recurrence, and severity of infections in Mexican patients with rheumatoid arthritis. 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