{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T11:18:48Z","timestamp":1778498328702,"version":"3.51.4"},"reference-count":77,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2009,9,10]],"date-time":"2009-09-10T00:00:00Z","timestamp":1252540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Adnexal tumours of the skin are benign, more rarely malignant, primary skin tumours that originate from, or differentiate towards, hair follicles, sebaceous and sweat glands. Although they are usually encountered as single, sporadic tumours, they may occasionally be multiple, hereditary; in that case, they may herald complex genetic syndromes that comprise visceral cancers. Dermatologists should be aware of these adnexal skin tumours, the diagnosis of which may contribute to an early detection of a cancer\u2010prone syndrome with a potentially lethal outcome. The main tumours falling into this category and their associated syndromes are reviewed here.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2009.03420.x","type":"journal-article","created":{"date-parts":[[2009,9,11]],"date-time":"2009-09-11T03:27:42Z","timestamp":1252639662000},"page":"379-387","source":"Crossref","is-referenced-by-count":19,"title":["Adnexal tumours of the skin as markers of cancer\u2010prone syndromes"],"prefix":"10.1111","volume":"24","author":[{"given":"J","family":"Kanitakis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,3,5]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(08)70126-8"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2004.025577"},{"key":"e_1_2_8_4_2","volume-title":"Atlas of Genodermatoses","author":"Caputo R","year":"2006"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2008.11.007"},{"key":"e_1_2_8_6_2","volume-title":"Pathology of the Skin With Clinical Correlations","author":"McKee","year":"2005"},{"key":"e_1_2_8_7_2","first-page":"412","article-title":"Cowden disease or multiple hamartomata syndrome \u2013 cutaneous clues to internal malignancy","volume":"12","author":"Fistarol S","year":"2002","journal-title":"Eur J Dermatol"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-58-1-136"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1984.tb00388.x"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(83)70081-2"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1986.tb00816.x"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1984.tb00389.x"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2003.12.049"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10897-008-9187-7"},{"key":"e_1_2_8_15_2","first-page":"133","article-title":"Linear Cowden nevus: a new distinct epidermal nevus","volume":"17","author":"Happle R","year":"2007","journal-title":"Eur J Dermatol"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.37.11.828"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2004.018036"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1086\/340026"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/humu.10257"},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-0922"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.06.026"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.4161\/cc.8.3.7555"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2007.07.009"},{"key":"e_1_2_8_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2008.07.011"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(05)70465-4"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20873"},{"key":"e_1_2_8_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70001-0"},{"key":"e_1_2_8_28_2","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/0002-9343(91)90637-D","article-title":"Association of sebaceous gland and internal malignancy: the Muir\u2010Torre syndrome","volume":"90","author":"Cohen P","year":"1991","journal-title":"Am J Med"},{"key":"e_1_2_8_29_2","doi-asserted-by":"publisher","DOI":"10.1086\/301926"},{"key":"e_1_2_8_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200203000-00007"},{"key":"e_1_2_8_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2009.01248.x"},{"key":"e_1_2_8_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djm291"},{"key":"e_1_2_8_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)90017-9"},{"key":"e_1_2_8_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2008.00247.x"},{"key":"e_1_2_8_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(85)70066-7"},{"key":"e_1_2_8_36_2","doi-asserted-by":"publisher","DOI":"10.1159\/000018399"},{"key":"e_1_2_8_37_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01648.x"},{"key":"e_1_2_8_38_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1995.tb01392.x"},{"key":"e_1_2_8_39_2","first-page":"139","article-title":"Multiple cutaneous and subcutaneous lesions occurring simultaneously with hereditary polyposis and osteomatosis","volume":"5","author":"Gardner E","year":"1953","journal-title":"Am J Hum Genet"},{"key":"e_1_2_8_40_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00375.x"},{"key":"e_1_2_8_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2008.04.012"},{"key":"e_1_2_8_42_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.31010"},{"key":"e_1_2_8_43_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-28032003000200006"},{"key":"e_1_2_8_44_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-9981-3"},{"key":"e_1_2_8_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1995.tb00195.x"},{"key":"e_1_2_8_46_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000213348.65014.0a"},{"key":"e_1_2_8_47_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10689-005-5673-3"},{"key":"e_1_2_8_48_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.9.1967"},{"key":"e_1_2_8_49_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-0297-0"},{"key":"e_1_2_8_50_2","doi-asserted-by":"publisher","DOI":"10.1159\/000099166"},{"key":"e_1_2_8_51_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30585"},{"key":"e_1_2_8_52_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10689-007-9161-9"},{"key":"e_1_2_8_53_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.2005.00519.x"},{"key":"e_1_2_8_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2006.07.004"},{"key":"e_1_2_8_55_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2006.01293.x"},{"key":"e_1_2_8_56_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10689-007-9158-4"},{"key":"e_1_2_8_57_2","doi-asserted-by":"publisher","DOI":"10.1067\/j.cpsurg.2005.01.004"},{"key":"e_1_2_8_58_2","doi-asserted-by":"publisher","DOI":"10.4065\/75.1.57"},{"key":"e_1_2_8_59_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10689-005-5674-2"},{"key":"e_1_2_8_60_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-4-96"},{"key":"e_1_2_8_61_2","first-page":"393","article-title":"Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt\u2010Hogg\u2010Dube syndrome","volume":"11","author":"Zbar B","year":"2002","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"e_1_2_8_62_2","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.5858\/2006-130-1865-BSCFAG","article-title":"Birt\u2010Hogg\u2010Dub\u00e9 syndrome. Clinicopathologic findings and genetic alterations","volume":"130","author":"Adley B","year":"2006","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_8_63_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700959"},{"key":"e_1_2_8_64_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2007.054304"},{"key":"e_1_2_8_65_2","doi-asserted-by":"publisher","DOI":"10.1067\/S0190-9622(03)01582-2"},{"key":"e_1_2_8_66_2","first-page":"53","article-title":"Multiple dermal perifollicular fibromas with polyps of the colon \u2013 report of a peculiar clinical syndrome","volume":"23","author":"Hornstein O","year":"1976","journal-title":"Acta Hepatogastroenterol"},{"key":"e_1_2_8_67_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1999.tb01792.x"},{"key":"e_1_2_8_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(02)00104-6"},{"key":"e_1_2_8_69_2","first-page":"382","article-title":"Birt\u2010Hogg\u2010Dub\u00e9 (BHD) syndrome: report of two novel germline mutations in the folliculin (FLCN) gene","volume":"18","author":"Palmirotta R","year":"2008","journal-title":"Eur J Dermatol"},{"key":"e_1_2_8_70_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800152"},{"key":"e_1_2_8_71_2","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2009.14"},{"key":"e_1_2_8_72_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003581"},{"key":"e_1_2_8_73_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cancergencyto.2007.10.010"},{"key":"e_1_2_8_74_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2007.049874"},{"key":"e_1_2_8_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.11.021"},{"key":"e_1_2_8_76_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02095.x"},{"key":"e_1_2_8_77_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2007.33270.x"},{"key":"e_1_2_8_78_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djm288"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2009.03420.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2009.03420.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T17:19:51Z","timestamp":1698945591000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2009.03420.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,5]]},"references-count":77,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["10.1111\/j.1468-3083.2009.03420.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2009.03420.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,5]]}}}