{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T06:25:31Z","timestamp":1769754331245,"version":"3.49.0"},"reference-count":18,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2011,2,23]],"date-time":"2011-02-23T00:00:00Z","timestamp":1298419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Cardiovascular risk factors have been assessed with some skin diseases such as alopecia and psoriasis. Recently, a case\u2013control study found that lichen planus (LP) was associated with dyslipidaemia in a large series of patients. However, no data were presented about lipid values in patients and controls.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> The objective of this case\u2013control study was to evaluate lipid levels in men and women with lichen planus and in healthy controls, excluding lichenoid drug eruption and treatment for LP such as systemic corticosteroids, retinoid acid or methotrexate.<\/jats:p><jats:p><jats:bold>Patients and methods\u2002<\/jats:bold> This case\u2013control study included 160 patients, 80 with LP (40 men and 40 women) and 80 controls consecutively admitted to the outpatient clinic in Dermatology department of San Cecilio Hospital, Granada, Spain.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Patients with LP presented higher significant triglycerides values (145.9 vs. 101.5\u2003mg\/dL <jats:italic>P\u2003<\/jats:italic>=\u20030.0007), total cholesterol values (197.7 vs. 178.4\u2003mg\/dL <jats:italic>P\u2003<\/jats:italic>=\u20030.001), LDL\u2010C values (120.8 vs. 100.9\u2003mg\/dL <jats:italic>P\u2003<\/jats:italic>&lt;\u20030.0001) and lower HDL\u2010C values (55.3 vs. 61.9\u2003mg\/dL <jats:italic>P\u2003<\/jats:italic>=\u20030.004) vs. controls. Adjusted OR for dyslipidaemia in patients with LP was 3.03 (95% confidence interval: 1.49\u20136.17, <jats:italic>P\u2003<\/jats:italic>=\u20030.002).<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> The results obtained in this study indicate an association between LP and dyslipidaemia. Lipid levels screening in men or women with LP may be useful to detect individuals at risk and start preventive treatment against the development of cardiovascular disease.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2011.03983.x","type":"journal-article","created":{"date-parts":[[2011,2,26]],"date-time":"2011-02-26T12:08:09Z","timestamp":1298722089000},"page":"1398-1401","source":"Crossref","is-referenced-by-count":37,"title":["Lipid levels in patients with lichen planus: a case\u2013control study"],"prefix":"10.1111","volume":"25","author":[{"given":"S.","family":"Arias\u2010Santiago","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Buend\u00eda\u2010Eisman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Aneiros\u2010Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.S.","family":"Gir\u00f3n\u2010Prieto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.T.","family":"Guti\u00e9rrez\u2010Salmer\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Garc\u00eda\u2010Mellado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Cutando","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Naranjo\u2010Sintes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,2,23]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09293.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09588.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.10.018"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04630.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07986.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.piel.2009.11.002"},{"key":"e_1_2_5_8_2","first-page":"12","article-title":"Prevalence of metabolic syndrome in patients with severe psoriasis","volume":"778","author":"Arias\u2010Santiago S","year":"2009","journal-title":"Actual Med"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09235.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015550310006851"},{"key":"e_1_2_5_11_2","first-page":"187","article-title":"Simvastatin\u2010induced lichen planus pemphigoides","volume":"130","author":"Stoebner PE","year":"2003","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0754"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02799-9"},{"key":"e_1_2_5_15_2","first-page":"108","article-title":"Widespread lichen planus in association with Turner\u2019s syndrome and multiple endocrinopathies","volume":"54","author":"Kurgansky D","year":"1994","journal-title":"Cutis"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1976.tb15530.x"},{"key":"e_1_2_5_17_2","first-page":"121","article-title":"Prevalence of diabetes mellitus amongst oral lichen planus patients. 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