{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T07:21:23Z","timestamp":1705562483407},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,3,2]],"date-time":"2011-03-02T00:00:00Z","timestamp":1299024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Flushing is defined clinically as a transient reddening of the face and other areas. Due to the transient nature of flushing, a patient may not show signs of flushing during laser treatment.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> The aim of this study was to evaluate the efficacy and safety of 595\u2010nm pulsed\u2010dye laser treatment of flushing or erythema after provocation of flushing by topical niacin cream.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> We retrospectively reviewed a total of 25 Korean patients with facial flushing who were treated with three sessions of 595\u2010nm pulsed\u2010dye laser after the application of topical niacin cream.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Follow\u2010up results revealed that 12 of the 25 patients demonstrated marked (51\u201375%) clinical improvement of baseline facial erythema. Eight patients had moderate (26\u201350%) improvement and three demonstrated near total (\u226575%) improvement. Two patients showed minimal to no (0\u201325%) improvement. We observed that the reactivity to topical niacin cream was markedly reduced in 64% of our patients after 595\u2010nm pulsed\u2010dye laser treatments. Minimal post\u2010therapy facial oedema was noted in most of the patients, which usually resolved spontaneously within 2\u2003days. Pronounced facial swelling was observed in four patients.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> We suggest that 595\u2010nm pulsed\u2010dye laser treatment after provocation of flushing by topical niacin cream may provide a new treatment algorithm for facial flushing in Asians.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2011.04006.x","type":"journal-article","created":{"date-parts":[[2011,3,2]],"date-time":"2011-03-02T15:20:14Z","timestamp":1299079214000},"page":"54-58","source":"Crossref","is-referenced-by-count":1,"title":["Topical niacin cream\u2010assisted 595\u2010nm pulsed\u2010dye laser treatment for facial flushing: retrospective analysis of 25 Korean patients"],"prefix":"10.1111","volume":"26","author":[{"given":"S.J.","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.R.","family":"Roh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.H.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.S.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.E.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.H.","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.B.","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,3,2]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(88)70177-2"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0738-081X(93)90057-J"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.07.057"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2005.31204"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2009.03386.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1473-2165.2005.00201.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08702.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.03.033"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.04.010"},{"key":"e_1_2_5_11_2","first-page":"522","article-title":"Flash lamp pumped dye laser for rosacea\u2010associated telangiectasia and erythema","volume":"17","author":"Lowe NJ","year":"1991","journal-title":"J Dermatol Surg Oncol"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-002-8263-8"},{"key":"e_1_2_5_13_2","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1111\/j.1742-1241.2001.tb11065.x","article-title":"The niacin skin flush test in schizophrenia: a replication study","volume":"55","author":"Puri BK","year":"2001","journal-title":"Int J Clin Pract"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2011.04006.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2011.04006.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T10:38:41Z","timestamp":1697366321000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2011.04006.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,2]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1111\/j.1468-3083.2011.04006.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2011.04006.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,2]]}}}