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Furthermore, Toll\u2010like receptors have also been implicated in the pathogenesis of several skin diseases such as skin infections, psoriasis, acne vulgaris, lichen planus, Beh\u00e7et\u2019s disease, leprosy, syphilis, Lyme disease, atopic dermatitis and allergic contact dermatitis, mycosis fungoides, non\u2010melanoma skin cancers and melanoma. In this manuscript, the structure and functions of Toll\u2010like receptors in immune responses, their impact on skin diseases and recent advances on therapeutic usage have been reviewed.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2011.04049.x","type":"journal-article","created":{"date-parts":[[2011,3,24]],"date-time":"2011-03-24T08:14:00Z","timestamp":1300954440000},"page":"997-1006","source":"Crossref","is-referenced-by-count":53,"title":["Toll\u2010like receptors and 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