{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:52:34Z","timestamp":1780404754620,"version":"3.54.1"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,4,15]],"date-time":"2011-04-15T00:00:00Z","timestamp":1302825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Animal studies have shown that many signs of acute poisoning result from phenol entry into the systemic circulation by absorption or ingestion. While no evidence of systemic complications in patients who have undergone phenol nail matrixectomies have been reported, the safety of phenol vapour inhalation by physicians performing this treatment has yet to be investigated.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> The goal of this study was to determine whether the levels of phenol to which physicians are exposed to during a phenol\u2010based matrixectomy procedure are within the limits of safe exposure.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> A continuous prospective study was carried out to measure the urinary phenol concentrations from physicians after performing chemical matrixectomy for ingrown toenails.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> The highest concentration of urinary phenol was measured at almost 10\u2003mg\/L within the first 2\u2003h after exposure, and subsequently decreased approximately 1\u2003mg\/L every 2\u2003h for the first 10\u2003h post exposure. The levels dropped to 3\u2003mg\/L at 72\u2003h post exposure.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> The risk associated with phenol exposure while performing chemical phenol matrixectomy was well below the current safety limits when the physician is exposed to 90% phenol vapour for approximately 20\u2003min. Thus, no further specific safety recommendations are required for physicians performing this procedure.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2011.04074.x","type":"journal-article","created":{"date-parts":[[2011,4,15]],"date-time":"2011-04-15T08:04:32Z","timestamp":1302854672000},"page":"344-347","source":"Crossref","is-referenced-by-count":5,"title":["Renal excretion of phenol from physicians after nail matrix phenolization: an observational prospective study"],"prefix":"10.1111","volume":"26","author":[{"given":"R.","family":"Becerro de Bengoa Vallejo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.E.","family":"Losa Iglesias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.T.","family":"Jules","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.","family":"Trepal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,4,15]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2001.01909.x"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2001.00150.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2010.03569.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.7547\/0980418"},{"key":"e_1_2_6_6_2","first-page":"70","article-title":"Quantitative relationship between atmospheric phenol vapour and phenol in the urine of workers in Bakelite factories","volume":"29","author":"Ohtsuji H","year":"1972","journal-title":"Br J Ind Med"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.3109\/00498259509061900"},{"key":"e_1_2_6_8_2","first-page":"172","article-title":"Evaluation of exposure to phenol: absorption of phenol vapour in the lungs and through the skin and excretion of phenol in urine","volume":"28","author":"Piotrowski JK","year":"1971","journal-title":"Br J Ind Med"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/oem.51.5.354"},{"key":"e_1_2_6_10_2","first-page":"570","volume-title":"The Extra Pharmacopoeia","author":"Reynolds J","year":"1993"},{"key":"e_1_2_6_11_2","unstructured":"ACGIH\u2010TLV.Threshold limit values for chemical substances and physical agents in the work environment and biological exposure indices with intended changes for 1984\u201085.1984."},{"key":"e_1_2_6_12_2","first-page":"2567","volume-title":"Toxicology:Industrial Hygiene and Toxicology","author":"Deichmann W","year":"1981"},{"key":"e_1_2_6_13_2","unstructured":"Instituto Nacional de Seguridad e Higiene en el Trabajo SMINdSeHeeT.Valores l\u00edmite biol\u00f3gicos para el control de exposici\u00f3n a compuestos org\u00e1nicos en Espa\u00f1a [Biological limit values for the control of exposure to organic compounds in Spain].2007: 234."},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/annhyg\/15.2-4.409"},{"key":"e_1_2_6_15_2","first-page":"303","article-title":"Management of the ingrown toenail","volume":"79","author":"Heidelbaugh JJ","year":"2009","journal-title":"Am Fam Physician"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2011.04074.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2011.04074.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T11:36:23Z","timestamp":1697369783000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2011.04074.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4,15]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["10.1111\/j.1468-3083.2011.04074.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2011.04074.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4,15]]}}}