{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T07:27:53Z","timestamp":1774682873199,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,4,27]],"date-time":"2011-04-27T00:00:00Z","timestamp":1303862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> During the last decades an increase has been observed regarding acne in adults and especially women.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> To evaluate the association between thyroid disorder and the presence of post\u2010adolescent acne in adult women, comparing with healthy controls.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> 107 adult women with post\u2013adolescent acne and 60 healthy controls were included. Complete blood count and standard biochemical profile of C\u2010Reactive Protein (CRP) and levels of thyroid hormones and antibodies [triiodothyronine (T3), thyroxine (T4), thyroid stimulating hormone (TSH), free T3 (FT3), free T4 (FT4), antithyroglobulin antibodies (anti\u2010TG) and anti\u2010thyroid peroxidase antibodies (anti\u2010TPO)] were determined in all subjects of both the acne and control groups. A thyroid ultrasound was also performed.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> There was a statistically significant difference (<jats:italic>P<\/jats:italic>\u2003=\u20030.008) in the prevalence of positive anti\u2010TG antibodies, with 25.2% of the acne group and 8.3% of the control group having elevated (&gt;\u200340\u2003U\/mL) anti\u2010TG levels, respectively. Adult women with acne had a statistically significant increased relative risk to have high levels of anti\u2010TG in comparison with healthy controls (odds ratio 3.89, <jats:italic>P<\/jats:italic>\u2003=\u20030.011). This association was independent of age. Values for TSH, FT4, FT3, T4 and anti\u2010TPO did not significantly differ between the two groups. No significant difference was found regarding the thyroid ultrasound findings. Although there was no significant difference between cases and controls regarding CRP levels, it is interesting that we observed a significant elevation in CRP in those acne patients who had positive antithyroglobulin antibodies.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> It is likely that thyroid autoimmunity might be more frequent in the adult acne patients and this should be kept in mind when screening women with post\u2010adolescent acne.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2011.04084.x","type":"journal-article","created":{"date-parts":[[2011,4,27]],"date-time":"2011-04-27T06:02:21Z","timestamp":1303884141000},"page":"413-416","source":"Crossref","is-referenced-by-count":19,"title":["Association of thyroid autoimmunity with acne in adult women"],"prefix":"10.1111","volume":"26","author":[{"given":"T.","family":"Vergou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Mantzou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Tseke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.E","family":"Moustou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Katsambas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Alevizaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Antoniou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,4,27]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1997.d01-1144.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)80056-5"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1990.tb03750.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03669.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000017861"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2494.2004.00210.x"},{"key":"e_1_2_5_8_2","first-page":"56","volume-title":"Acne Diagnosis and Management","author":"Cunliffe WJ","year":"2001"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.06.045"},{"key":"e_1_2_5_10_2","first-page":"S3","article-title":"Management of adult acne and acne variants","volume":"2","author":"Cunliffe WJ","year":"1998","journal-title":"J Cutan Med Surg"},{"key":"e_1_2_5_11_2","article-title":"Sebum excretion rate in post\u2010adolescent acne compared to controls and adolescent acne","volume":"108","author":"McGeown CH","year":"1997","journal-title":"J Invest Dermatol"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1500363"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2009.09.004"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.1995.tb00057.x"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2009.01.001"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2011.04084.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2011.04084.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T09:33:42Z","timestamp":1697362422000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2011.04084.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4,27]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["10.1111\/j.1468-3083.2011.04084.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2011.04084.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4,27]]}}}