{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T07:41:56Z","timestamp":1697442116719},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,5,4]],"date-time":"2011-05-04T00:00:00Z","timestamp":1304467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Cutaneous Herpes simplex virus (HSV) infections are regularly observed in lumbosacral areas, and many are refractory to appropriate initial diagnosis and management.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> We aimed to evaluate the incidence of lumbosacral HSV among advanced disease patients, to estimate their survival index from HSV onset, and to describe their clinical and virological characteristics.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> A prospective, descriptive study was conducted in a palliative and continuous care centre, collecting patients with suspected cutaneous HSV lesions in the lumbosacral area.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> From 2008 to 2010, 24 patients were included: 19 had HSV\u20102 confirmed by at least one laboratory test. Incidence of HSV\u20102 was 2.67% (1.73\u20134.33%, 95% CI). No age, gender or survival differences were observed compared to the global population in the centre. Most lesions were detected early as vesicles (14\/24) or small ulcers. Sensitivity was good for all diagnostic methods (62.5% for immunofluorescence and 79.2% for culture and\/or PCR). Outcome was favourable under classical antiherpetic drugs and topical antiseptic dressing.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Cutaneous lumbosacral HSV remains uncommon in patients hospitalized with advanced diseases. Most of these patients suffer from pressure ulcers or other dermatitis; we advocate increased attention of this diagnosis to avoid skin complications and added pain.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2011.04085.x","type":"journal-article","created":{"date-parts":[[2011,5,4]],"date-time":"2011-05-04T08:23:00Z","timestamp":1304497380000},"page":"417-422","source":"Crossref","is-referenced-by-count":2,"title":["Cutaneous lumbosacral Herpes Simplex virus among patients hospitalized for an advanced 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