{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:48:47Z","timestamp":1772160527963,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,5,13]],"date-time":"2011-05-13T00:00:00Z","timestamp":1305244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Background\u2002<\/jats:bold>\n                    Mastocytoses represent a heterogeneous group of stem cell disorders marked by an abnormal hyperplasia and accumulation of mast cells in one or more tissues, including bone marrow, gastrointestinal tract, liver, spleen, lymph nodes and skin. Indolent systemic mastocytosis (ISM) is characterized by red\u2010brownish and pruriginous maculopapular lesions, a bone marrow infiltration without functional impairment and an indolent clinical course with a good prognosis. In particular, the most common cutaneous symptoms are urticarial rash and mild\u2010to\u2010high pruritus.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Objectives\u2002<\/jats:bold>\n                    This study analyses the clinical outcome of patients affected by ISM with prevalent pruriginous cutaneous symptoms and a scarce response to anti\u2010histamines treated using narrowband ultraviolet B (NB\u2010UVB) phototherapy.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods\u2002<\/jats:bold>\n                    Narrowband ultraviolet B phototherapy was administered in a UV\u2010irradiation cabin equipped with fluorescent UVB lamps with a peak emission at 311\u2013313\u2003nm. The perception of pruritus severity was assessed using the Visual Analogue Scale (VAS) before starting the treatment and at each control.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results\u2002<\/jats:bold>\n                    A complete remission of the cutaneous lesions and pruritus was documented in all patients after a median of 40.3 UV treatments and a median cumulative dose of 51.4\u2003J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    , with a lasting remission over a 6\u2010month follow\u2010up. The median VAS score at the beginning of the treatment was 86.6 (SD\u2003=\u20036.64), whereas it decreased to 6.66 (SD\u2003=\u20033.75) after 3\u2003months of therapy.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions\u2002<\/jats:bold>\n                    Our work provides evidence that NB\u2010UVB phototherapy is useful for the treatment of the cutaneous symptoms and pruritus in ISM.\n                  <\/jats:p>","DOI":"10.1111\/j.1468-3083.2011.04098.x","type":"journal-article","created":{"date-parts":[[2011,5,13]],"date-time":"2011-05-13T02:57:28Z","timestamp":1305255448000},"page":"465-469","source":"Crossref","is-referenced-by-count":20,"title":["Indolent systemic mastocytosis treated with narrow\u2010band UVB phototherapy: study of five 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