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A systematic review of current literature on the various treatment modalities for primary focal hyperhidrosis was performed and a step\u2010by\u2010step approach for the different types of primary focal hyperhidrosis (axillary, palmar, plantar and craniofacial) was established. Non\u2010surgical treatments (aluminium salts, local and systemic anticholinergics, botulinum toxin A (BTX\u2010A) injections and iontophoresis) are adequately supported by the current literature. More invasive surgical procedures (suction curettage and sympathetic denervation) have also been extensively investigated, and can offer a more definitive solution for cases of hyperhidrosis that are unresponsive to non\u2010surgical treatments. There is no consensus on specific techniques for sympathetic denervation, and this issue should be further examined by meta\u2010analysis. There are numerous treatment options available to improve the quality of life (QOL) of the hyperhidrosis patient. 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