{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T10:47:07Z","timestamp":1790938027238,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2011,8,4]],"date-time":"2011-08-04T00:00:00Z","timestamp":1312416000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Female pattern hair loss (FPHL) is the most common cause of hair loss in women, and its prevalence increases with advancing age. Affected women may experience psychological distress and social withdrawal. A variety of laser and light sources have been tried for treatment of hair loss, and some success has been reported.<\/jats:p><jats:p><jats:bold>Objective\u2002<\/jats:bold> The purpose of this study was to determine the efficacy and safety of a 1550\u2003nm fractional erbium\u2013glass laser in treatment of female pattern hair loss.<\/jats:p><jats:p><jats:bold>Patients and methods\u2002<\/jats:bold> Twenty eight ethnic South Korean patients with varying degrees of FPHL were enrolled in the study. Patients received ten treatments with a 1550\u2003nm fractional Er:Glass Laser (Mosaic, Lutronic Co., Ltd, Seoul, South Korea) at 2\u2010weeks intervals using the same parameters (5\u201310\u2003mm tip, 6\u2003mJ pulse energy, 800 spot\/cm<jats:sup>2<\/jats:sup> density, static mode). Phototrichogram and global photographs were taken at baseline and at the end of laser treatment, and analysed for changes in hair density and hair shaft diameter. Global photographs underwent blinded review by three independent dermatologists using a 7\u2010point scale. Patients also answered questionnaires assessing hair growth throughout the study. All adverse effects were reported during the study.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Twenty seven patients completed a 5\u2010month schedule of laser treatment. One patient was excluded during treatment due to occurrence of alopecia areata. At the initial visit, mean hair density was 100\u2003\u00b1\u200314\/cm<jats:sup>2<\/jats:sup>, and mean hair thickness was 58\u2003\u00b1\u200312\u2003\u03bcm. After 5\u2003months of laser treatment, hair density showed a marked increase to 157\u2003\u00b1\u200328\/cm<jats:sup>2<\/jats:sup> (<jats:italic>P\u2003&lt;\u2003<\/jats:italic>0.001), and hair thickness also increased to 75\u2003\u00b1\u200313\u2003\u03bcm (<jats:italic>P\u2003&lt;\u2003<\/jats:italic>0.001). Global photographs showed improvement in 24 (87.5%) of the 27 patients. Two patients (7.4%) reported mild pruritus after laser treatment; however, these resolved within 2\u2003h.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> A 1550\u2003nm fractional erbium\u2013glass laser irradiation may be an effective and safe treatment option for women with female pattern hair loss.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2011.04183.x","type":"journal-article","created":{"date-parts":[[2011,8,4]],"date-time":"2011-08-04T07:27:30Z","timestamp":1312442850000},"page":"1450-1454","source":"Crossref","is-referenced-by-count":77,"title":["The effect of a 1550\u2003nm fractional erbium\u2013glass laser in female pattern hair loss"],"prefix":"10.1111","volume":"25","author":[{"given":"G.\u2010Y.","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.\u2010J.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.\u2010S.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,8,4]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"189","article-title":"Female pattern hair loss: current treatment concepts","volume":"2","author":"Dinh QQ","year":"2007","journal-title":"Clin Interv Aging"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.117426"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2010.07261_supp.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2009.01.001"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04289.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/14764170601134479"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20002"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000265678"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/14764170902842531"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2002.02101.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/09546630802178224"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/14764170600607368"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.06.054"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05766"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/177791b0"},{"key":"e_1_2_5_17_2","first-page":"575","article-title":"Regeneration of hair follicles and sebaceous glands from epithelium of scars in the rabbit","volume":"14","author":"Breedis C","year":"1954","journal-title":"Cancer Res"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2008.071177"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/SMJ.0b013e3181ebcf71"},{"key":"e_1_2_5_20_2","first-page":"42","article-title":"Update on fractional laser technology","volume":"3","author":"Gold MH","year":"2010","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2008.01.002"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2003.83.3.835"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2006.01.002"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2011.04183.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2011.04183.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T03:42:03Z","timestamp":1697341323000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2011.04183.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8,4]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["10.1111\/j.1468-3083.2011.04183.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2011.04183.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,8,4]]}}}