{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:32:23Z","timestamp":1792099943291,"version":"4.4.0"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,7,3]],"date-time":"2012-07-03T00:00:00Z","timestamp":1341273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Background\u2002<\/jats:bold>\n                    Alopecia areata (AA) is an autoimmune disease affecting about 2% of the population, which has a considerable impact on quality of life (QoL). There are no disease\u2010specific questionnaires to assess QoL in patients suffering from AA.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Objective\u2002<\/jats:bold>\n                    To validate a new disease\u2010specific questionnaire for AA, named AA\u2010QLI, and to compare the consequent Quality of Life Index (QLI) with the commonly known Dermatology Life Quality Index (DLQI) to verify if it can provide a more comprehensive tool for patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods\u2002<\/jats:bold>\n                    A total of 50 patients affected by AA were administered both the AA\u2010QLI, created by us, and the well\u2010known DLQI. With the aim to detect suitable QLI, we propose to use two multivariate analyses:\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:list list-type=\"explicit-label\">\n                      <jats:list-item>\n                        <jats:p>\u2002a principal component analysis approach on the data collected with both questionnaires to compare their capability to measure the QoL;<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>\u2002a structural equation modelling on our AA\u2010QLI to identify which category of symptoms mostly affects the QoL.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results\u2002<\/jats:bold>\n                    The scores of both the questionnaires are quite close, except for a few cases. Statistical analysis shows a higher specificity of the AA\u2010QLI for evaluating QoL. Among the three areas in which AA\u2010QLI is divided, \u2018Relationship\u2019 has a major impact on the QLI, followed by \u2018Subjective symptoms\u2019; \u2018Objective signs\u2019 has a lower weight on the QLI.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion\u2002<\/jats:bold>\n                    AA\u2010QLI is a good instrument to evaluate the real impact of AA on QoL. It can be helpful both for the physician and for the patient.\n                  <\/jats:p>","DOI":"10.1111\/j.1468-3083.2012.04629.x","type":"journal-article","created":{"date-parts":[[2012,7,3]],"date-time":"2012-07-03T06:05:24Z","timestamp":1341295524000},"source":"Crossref","is-referenced-by-count":73,"title":["Quality of life in alopecia areata: a disease\u2010specific questionnaire"],"prefix":"10.1111","volume":"27","author":[{"given":"G.","family":"Fabbrocini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Panariello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"De Vita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Vincenzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Lauro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Nappo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Ayala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Tosti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,7,3]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"364","article-title":"Alopecia areata: autoimmune basis of hair loss","volume":"14","author":"Alexis AF","year":"2004","journal-title":"Eur J Dermatol"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1087-0024.2004.00835.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2005.07.001"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2009.09.008"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2005.10130_3.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1086\/511442"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI31942"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10466.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2011.01411.x"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2011.01.007"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.02.006"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2004.09.014"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08818.x"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5701183"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2003.tb00341.x"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02028.x"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.02106.x"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.02748.x"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2010.09057"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2010.232"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01167.x"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1997.d01-1169.x"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)70210-X"},{"key":"e_1_2_5_25_2","first-page":"39","article-title":"Quaviderm: un questionario per la valutazione della qualit\u00e0 di vita italiana in dermatologia","volume":"51","author":"Lisi P","year":"1997","journal-title":"Ann Ital Dermatol Clin Sper"},{"key":"e_1_2_5_26_2","volume-title":"An outline of PRINCALS","author":"Van Rijckevorsel J","year":"1979"},{"key":"e_1_2_5_27_2","first-page":"231","volume-title":"Data Analysis and Informatics","author":"DeLeeuw J","year":"1980"},{"key":"e_1_2_5_28_2","volume-title":"SEM with Ordinal Manifest Variables. 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