{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T01:18:06Z","timestamp":1784423886549,"version":"3.55.0"},"reference-count":4,"publisher":"Wiley","issue":"s6","license":[{"start":{"date-parts":[[2012,10,16]],"date-time":"2012-10-16T00:00:00Z","timestamp":1350345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 9\u2010month\u2010old infant, with no family history of atopy, presenting with erythematous, itchy plaques, and sleep disturbance, was diagnosed with atopic eczema (AE). Previous treatment with topical hydrocortisone and emollients had little effect. The infant was treated nightly with methylprednisolone aceponate (MPA) 0.1% (Advantan<jats:sup>\u00ae<\/jats:sup>) cream, in addition to emollients and an oral antihistamine. After 1 week of once\u2010daily MPA 0.1% treatment, followed by 1 week of alternate\u2010day treatment with Advantan, significant improvements in AE symptoms and sleep were observed. The patient's caregiver reported overall treatment satisfaction and no side effects of Advantan. For this infant with newly diagnosed AE, Advantan improved symptoms and sleep quality in a safe and well\u2010tolerated manner.<\/jats:p>","DOI":"10.1111\/j.1468-3083.2012.04712.x","type":"journal-article","created":{"date-parts":[[2012,10,16]],"date-time":"2012-10-16T08:41:49Z","timestamp":1350376909000},"page":"14-15","source":"Crossref","is-referenced-by-count":5,"title":["Effective use of methylprednisolone aceponate 0.1% in a 9\u2010month\u2010old infant with atopic eczema and sleep disturbance"],"prefix":"10.1111","volume":"26","author":[{"given":"S.","family":"Machado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,16]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(94)70004-4"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.03.045"},{"key":"e_1_2_8_4_2","doi-asserted-by":"crossref","first-page":"4","DOI":"10.5070\/D35HX776QP","article-title":"Atopic dermatitis, innate immunity and infection","volume":"17","author":"Lopes C","year":"2011","journal-title":"Dermatol Online J"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp042803"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1468-3083.2012.04712.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2012.04712.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/j.1468-3083.2012.04712.x","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1468-3083.2012.04712.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T09:23:31Z","timestamp":1693819411000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1468-3083.2012.04712.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,16]]},"references-count":4,"journal-issue":{"issue":"s6","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.1111\/j.1468-3083.2012.04712.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1468-3083.2012.04712.x","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,16]]}}}