{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T21:59:19Z","timestamp":1775080759384,"version":"3.50.1"},"reference-count":17,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,11,30]],"date-time":"2014-11-30T00:00:00Z","timestamp":1417305600000},"content-version":"vor","delay-in-days":3712,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalmicrobiologyandinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2004,10]]},"DOI":"10.1111\/j.1469-0691.2004.00958.x","type":"journal-article","created":{"date-parts":[[2004,9,16]],"date-time":"2004-09-16T11:08:22Z","timestamp":1095332902000},"page":"925-928","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"title":["Efficacy of voriconazole plus amphotericin B or micafungin in a guinea-pig model of invasive pulmonary aspergillosis"],"prefix":"10.1016","volume":"10","author":[{"given":"P.H.","family":"Chandrasekar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.L.","family":"Cutright","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.K.","family":"Manavathu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1111\/j.1469-0691.2004.00958.x_bib1","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1086\/513943","article-title":"Invasive aspergillosis","volume":"26","author":"Denning","year":"1998","journal-title":"Clin Infect Dis"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib2","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1086\/322606","article-title":"Trends in mortality due to invasive mycotic diseases in the United States","volume":"33","author":"McNeil","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib3","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1097\/00005792-200007000-00006","article-title":"Invasive aspergillosis: disease spectrum, treatment practices, and outcomes","volume":"79","author":"Patterson","year":"2002","journal-title":"Medicine (Baltimore)"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib4","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1056\/NEJMoa020191","article-title":"Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis","volume":"347","author":"Herbrecht","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib5","series-title":"Program and abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego","first-page":"388","article-title":"Multicenter, non-comparative study to evaluate safety and efficacy of caspofungin (CAS) in adults with invasive aspergillosis (IA) refractory (R) or intolerant (I) to amphotericin B (AMB), AMB lipid formulations (Lipid AMB) or azoles [abstract M-868]","author":"Maertens","year":"2002"},{"issue":"suppl 2","key":"10.1111\/j.1469-0691.2004.00958.x_bib6","first-page":"2","article-title":"In vitro susceptibility of Aspergillus fumigatus to conventional and lipid formulations of amphotericin B in 2-drug combination with caspofungin and micafungin","volume":"6","author":"Chandrasekar","year":"2002","journal-title":"Int J Infect Dis"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib7","series-title":"Program and abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago","first-page":"364","article-title":"In vitro antifungal activity of voriconazole in two-drug combination with micafungin, caspofungin and amphotericin B [abstract J-125]","author":"Manavathu","year":"2001"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib8","series-title":"Program and abstracts of the 40th Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto","first-page":"368","article-title":"In vitro synergy studies with caspofungin and amphotericin B against Aspergillus and Fusarium [abstract 932]","author":"Arikan","year":"2000"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib9","doi-asserted-by":"crossref","first-page":"2564","DOI":"10.1128\/AAC.46.8.2564-2568.2002","article-title":"Efficacy of caspofungin alone and in combination with voriconazole in a guinea pig model of invasive aspergillosis","volume":"46","author":"Kirkpatrick","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib10","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1093\/jac\/45.5.673","article-title":"Efficacy of voriconazole against invasive pulmonary aspergillosis in a guinea-pig model","volume":"45","author":"Chandrasekar","year":"2000","journal-title":"J Antimicrob Chemother"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib11","first-page":"904","article-title":"Use of ketamine hydrochloride as an anesthetic in laboratory rabbits, rats, mice and guinea pigs","volume":"22","author":"Weisbroth","year":"1972","journal-title":"Lab Anim Sci"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib12","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1093\/infdis\/151.5.902","article-title":"The effect of ketoconazole on amphotericin B in a model of disseminated aspergillosis","volume":"15","author":"Schaffner","year":"1985","journal-title":"J Infect Dis"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib13","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1439-0507.1993.tb00732.x","article-title":"Amphotericin B refractory aspergillosis after itraconazole: evidence for significant antagonism","volume":"36","author":"Schaffner","year":"1993","journal-title":"Mycoses"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib14","series-title":"Program and abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego","first-page":"416","article-title":"Efficacy and toxicity of the caspofungin\/liposomal amphotericin B combination in documented or possible invasive aspergillosis in patients with hematologic malignancies [abstract M-1820]","author":"Kontoyiannis","year":"2002"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib15","series-title":"Abstracts of the 44th Annual Meeting of the American Society of Hematology","first-page":"627","article-title":"Micafungin in combination with systemic antifungal agents in the treatment of refractory aspergillosis in bone marrow transplant patients [abstract 2472]","author":"Ratanatharathorn","year":"2002"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib16","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1002\/cncr.11115","article-title":"Refractory aspergillus pneumonia in patients with acute leukemia: successful therapy with combination caspofungin and liposomal amphotericin","volume":"97","author":"Aliff","year":"2003","journal-title":"Cancer"},{"key":"10.1111\/j.1469-0691.2004.00958.x_bib17","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1086\/375420","article-title":"Combination therapy in treatment of experimental pulmonary aspergillosis: synergistic interaction between an antifungal triazole and an echinocandin","volume":"187","author":"Petraitis","year":"2003","journal-title":"J Infect Dis"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X14633620?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X14633620?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T07:18:10Z","timestamp":1761117490000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X14633620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10]]},"references-count":17,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2004,10]]}},"alternative-id":["S1198743X14633620"],"URL":"https:\/\/doi.org\/10.1111\/j.1469-0691.2004.00958.x","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2004,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of voriconazole plus amphotericin B or micafungin in a guinea-pig model of invasive pulmonary aspergillosis","name":"articletitle","label":"Article Title"},{"value":"Clinical Microbiology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/j.1469-0691.2004.00958.x","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 European Society of Clinical Infectious Diseases. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}