{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:43:20Z","timestamp":1762865000489,"version":"build-2065373602"},"reference-count":42,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,11,30]],"date-time":"2014-11-30T00:00:00Z","timestamp":1417305600000},"content-version":"vor","delay-in-days":3316,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalmicrobiologyandinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1111\/j.1469-0691.2005.01260.x","type":"journal-article","created":{"date-parts":[[2005,10,7]],"date-time":"2005-10-07T10:19:43Z","timestamp":1128680383000},"page":"919-924","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Nosocomial bloodstream infections caused by Streptococcus pneumoniae"],"prefix":"10.1016","volume":"11","author":[{"given":"E.","family":"Bouza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Pintado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Rivera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Bl\u00e1zquez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Cercenado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Loza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Rodr\u00edguez-Cr\u00e9ixems","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Moreno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1111\/j.1469-0691.2005.01260.x_bib1","first-page":"2362","article-title":"Nosocomial infections with penicillin-resistant Streptococcus pneumoniae. Four clusters with pneumococci serotype 9V","volume":"163","author":"Folkersen","year":"2001","journal-title":"Ugeskr Laeger"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib2","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s100960000361","article-title":"Prognostic factors for pneumococcal bacteremia in a university hospital","volume":"19","author":"Farinas-Alvarez","year":"2000","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib3","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1086\/520148","article-title":"Identification of clinical risk factors for nosocomial pneumococcal bacteremia","volume":"29","author":"Rubins","year":"1999","journal-title":"Clin Infect Dis"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib4","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1001\/archinte.1986.00360200059010","article-title":"Nosocomial pneumococcal bacteremia","volume":"146","author":"Alvarez","year":"1986","journal-title":"Arch Intern Med"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib5","first-page":"265","article-title":"Comparison of community-acquired and nosocomial pneumococcal bacteremia","volume":"123","author":"Mylotte","year":"1981","journal-title":"Am Rev Respir Dis"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib6","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/0002-9343(84)90193-1","article-title":"Pneumococcal bacteremia at a medical\/surgical hospital for adults between 1975 and 1980","volume":"77","author":"Ruben","year":"1984","journal-title":"Am J Med"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib7","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1111\/j.1532-5415.1987.tb06353.x","article-title":"Pneumococcal bacteremia. Update from an adult hospital with a high rate of nosocomial cases","volume":"35","author":"Chang","year":"1987","journal-title":"J Am Geriatr Soc"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib8","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1086\/342335","article-title":"Hospital-acquired pneumococcal bacteremia","volume":"35","author":"Canet","year":"2002","journal-title":"Clin Infect Dis"},{"year":"2003","series-title":"Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 6th edn. Approved standard M07-A6. MIC testing supplementary tables","author":"National Committee for Clinical Laboratory Standards","key":"10.1111\/j.1469-0691.2005.01260.x_bib9"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib10","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/0196-6553(88)90053-3","article-title":"CDC definitions for nosocomial infections, 1988","volume":"16","author":"Garner","year":"1988","journal-title":"Am J Infect Cont"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib11","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0195-6701(98)90237-7","article-title":"Review of case definitions for nosocomial infection\u2014towards a consensus. Presentation by the Nosocomial Infection Surveillance Unit (NISU) to the Hospital Infection Liaison Group, subcommittee of the Federation of Infection Societies (FIS)","volume":"39","author":"Crowe","year":"1998","journal-title":"J Hosp Infect"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib12","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1001\/archinte.1962.03620240029006","article-title":"Gram-negative bacteremia I. Etiology and ecology","volume":"110","author":"McCabe","year":"1962","journal-title":"Arch Intern Med"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib13","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J Chronic Dis"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib14","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1097\/00003246-198510000-00009","article-title":"APACHE II: a severity of disease classification system","volume":"13","author":"Knaus","year":"1985","journal-title":"Crit Care Med"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib15","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1378\/chest.101.6.1644","article-title":"Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP\/SCCM Consensus Conference Committee. American College of Chest Physicians\/Society of Critical Care Medicine","volume":"101","author":"Bone","year":"1992","journal-title":"Chest"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib16","first-page":"384","article-title":"An epidemic of cold, bronchitis and pneumonia due to type V pneumococci","volume":"46","author":"Schroeder","year":"1930","journal-title":"J Infect Dis"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib17","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1001\/jama.1941.02820140009003","article-title":"Pneumococcic pneumonia complicating operations and trauma","volume":"116","author":"Stoneburner","year":"1941","journal-title":"JAMA"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib18","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1056\/NEJM199301073280104","article-title":"Acute bacterial meningitis in adults. A review of 493 episodes","volume":"328","author":"Durand","year":"1993","journal-title":"N Engl J Med"},{"issue":"suppl C","key":"10.1111\/j.1469-0691.2005.01260.x_bib19","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/jac\/25.suppl_C.41","article-title":"The causative organisms of septicaemia and their epidemiology","volume":"25","author":"Eykyn","year":"1990","journal-title":"J Antimicrob Chemother"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib20","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0163-4453(95)91147-2","article-title":"Microbiology of nosocomial sinusitis in intensive care unit patients","volume":"31","author":"Bert","year":"1995","journal-title":"J Infect"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib21","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/S0196-6553(96)90026-7","article-title":"National Nosocomial Infections Surveillance (NNIS) report, data summary from October 1986\u2013April 1996, issued May 1996. A report from the National Nosocomial Infections Surveillance (NNIS) System","volume":"24","author":"Anonymous","year":"1996","journal-title":"Am J Infect Cont"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib22","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1056\/NEJM199508243330802","article-title":"Resistance to penicillin and cephalosporin and mortality from severe pneumococcal pneumonia in Barcelona, Spain","volume":"333","author":"Pallares","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib23","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1093\/clinids\/14.2.427","article-title":"Susceptibility of Streptococcus pneumoniae to penicillin: a prospective microbiological and clinical study","volume":"14","author":"Garcia-Leoni","year":"1992","journal-title":"Clin Infect Dis"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib24","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1086\/647877","article-title":"Is Streptococcus pneumoniae a nosocomially acquired pathogen?","volume":"19","author":"Paradisi","year":"1998","journal-title":"Infect Cont Hosp Epidemiol"},{"issue":"suppl 4","key":"10.1111\/j.1469-0691.2005.01260.x_bib25","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1046\/j.1469-0691.2001.00056.x","article-title":"Streptococcus pneumoniae as an agent of nosocomial infection: treatment in the era of penicillin-resistant strains","volume":"7","author":"Paradisi","year":"2001","journal-title":"Clin Microbiol Infect"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib26","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.1532-5415.1981.tb01272.x","article-title":"Nosocomial pneumococcal pneumonia in the elderly","volume":"29","author":"Berk","year":"1981","journal-title":"J Am Geriatr Soc"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib27","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/0195-6701(87)90055-7","article-title":"A prospective survey of hospital cross-infection with Streptococcus pneumoniae","volume":"9","author":"Davies","year":"1987","journal-title":"J Hosp Infect"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib28","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1097\/01.inf.0000076547.55195.28","article-title":"Increased incidence of pneumococcal bloodstream infections","volume":"22","author":"Rodriguez-Creixems","year":"2003","journal-title":"Pediatr Infect Dis J"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib29","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1080\/00365549850160891","article-title":"Bacteraemic pneumococcal infections in Southern Sweden 1981\u201396: trends in incidence, mortality, age-distribution, serogroups and penicillin-resistance","volume":"30","author":"Ekdahl","year":"1998","journal-title":"Scand J Infect Dis"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib30","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1001\/archinte.1990.00390190067009","article-title":"Pneumococcal bacteremia in Charleston County, South Carolina. A decade later","volume":"150","author":"Breiman","year":"1990","journal-title":"Arch Intern Med"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib31","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3109\/00365549509019017","article-title":"Bacteremia at a Danish university hospital during a twenty-five-year period (1968\u201392)","volume":"27","author":"Arpi","year":"1995","journal-title":"Scand J Infect Dis"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib32","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.1001\/jama.1992.03490230053027","article-title":"Epidemiology of invasive pneumococcal infections in children in Finland","volume":"268","author":"Eskola","year":"1992","journal-title":"JAMA"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib33","doi-asserted-by":"crossref","first-page":"3328","DOI":"10.1001\/jama.1992.03490230058028","article-title":"Epidemiology of invasive childhood pneumococcal infections in Israel. The Israeli Pediatric Bacteremia and Meningitis Group","volume":"268","author":"Dagan","year":"1992","journal-title":"JAMA"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib34","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0025-7753(01)72076-3","article-title":"Pneumococcal bacteremia in patients aged over 65 years. A study of 161 cases","volume":"117","author":"Vaqueiro Subirats","year":"2001","journal-title":"Med Clin (Barc)"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib35","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1086\/377534","article-title":"An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome","volume":"37","author":"Yu","year":"2003","journal-title":"Clin Infect Dis"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib36","doi-asserted-by":"crossref","first-page":"M9","DOI":"10.1093\/geronj\/43.1.M9","article-title":"Nosocomial infections in long-term facilities","volume":"43","author":"Alvarez","year":"1988","journal-title":"J Gerontol"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib37","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/00005792-200007000-00002","article-title":"Bacteremic and nonbacteremic pneumococcal pneumonia. A prospective study","volume":"79","author":"Musher","year":"2000","journal-title":"Medicine (Baltimore)"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib38","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1086\/313716","article-title":"Impact of penicillin susceptibility on medical outcomes for adult patients with bacteremic pneumococcal pneumonia","volume":"30","author":"Metlay","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib39","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/S0099-1767(99)70154-6","article-title":"Fulminate pneumococcal septicemia in the asplenic patient: a case study with urgent implications for recognition and prevention","volume":"25","author":"Steffen","year":"1999","journal-title":"J Emerg Nurs"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib40","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/00006454-199901000-00010","article-title":"Clinical implications of penicillin and ceftriaxone resistance among children with pneumococcal bacteremia","volume":"18","author":"Silverstein","year":"1999","journal-title":"Pediatr Infect Dis J"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib41","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1001\/archinte.161.15.1837","article-title":"Monotherapy may be suboptimal for severe bacteremic pneumococcal pneumonia","volume":"161","author":"Waterer","year":"2001","journal-title":"Arch Intern Med"},{"key":"10.1111\/j.1469-0691.2005.01260.x_bib42","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1086\/367541","article-title":"Addition of a macrolide to a beta-lactam-based empirical antibiotic regimen is associated with lower in-hospital mortality for patients with bacteremic pneumococcal pneumonia","volume":"36","author":"Martinez","year":"2003","journal-title":"Clin Infect Dis"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X14626094?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X14626094?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T07:16:19Z","timestamp":1761117379000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X14626094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":42,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S1198743X14626094"],"URL":"https:\/\/doi.org\/10.1111\/j.1469-0691.2005.01260.x","relation":{},"ISSN":["1198-743X"],"issn-type":[{"type":"print","value":"1198-743X"}],"subject":[],"published":{"date-parts":[[2005,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nosocomial bloodstream infections caused by Streptococcus pneumoniae","name":"articletitle","label":"Article Title"},{"value":"Clinical Microbiology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/j.1469-0691.2005.01260.x","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 European Society of Clinical Infectious Diseases. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}