{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T13:34:36Z","timestamp":1791120876388,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,11,30]],"date-time":"2014-11-30T00:00:00Z","timestamp":1417305600000},"content-version":"vor","delay-in-days":2494,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1111\/j.1469-0691.2007.01889.x","type":"journal-article","created":{"date-parts":[[2010,9,13]],"date-time":"2010-09-13T12:05:01Z","timestamp":1284379501000},"page":"168-173","source":"Crossref","is-referenced-by-count":44,"title":["Detection of new genotypes of Orientia tsutsugamushi infecting humans in Thailand"],"prefix":"10.1016","volume":"14","author":[{"given":"P.-E.","family":"Fournier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Siritantikorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-M.","family":"Rolain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Suputtamongkol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Hoontrakul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Charoenwat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Losuwanaluk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Parola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Raoult","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/j.1469-0691.2007.01889.x_bib1","series-title":"Tsutsugamushi disease","year":"1995"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.4269\/ajtmh.1994.50.219","article-title":"An ultrastructural study of vertical transmission ofRickettsia tsutsugamushi during oogenesis and spermatogenesis inLeptotrombidium pallidium","volume":"50","author":"Urakami","year":"1994","journal-title":"Am J Trop Med Hyg"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib3","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1017\/S0031182099005909","article-title":"Transmission ofOrientia tsutsugamushi, the aetiological agent for scrub typhus, to co\u2010feeding mites","volume":"120","author":"Frances","year":"2000","journal-title":"Parasitology"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib4","first-page":"360","article-title":"Chigger mite infestation of small mammals in a feral biotope of a public park area of south Delhi","volume":"21","author":"Saxena","year":"1989","journal-title":"J Commun Dis"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib5","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0923-2508(96)80284-1","article-title":"Phylogenetic analysis of the genusRickettsia by 16S rDNA sequencing","volume":"146","author":"Roux","year":"1995","journal-title":"Res Microbiol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib6","first-page":"308","article-title":"Identification and serological classification of the causative agent of scrub typhus in Japan","volume":"15","author":"Shishido","year":"1962","journal-title":"Japn J Sci Biol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib7","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1111\/j.1348-0421.1986.tb02988.x","article-title":"Immunological properties ofRickettsia tsutsugamushi, Kawasaki strain, isolated from a patient in Kyushu","volume":"30","author":"Yamamoto","year":"1986","journal-title":"Microbiol Immunol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib8","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1128\/JCM.28.9.2111-2113.1990","article-title":"Characterization of a new antigenic type, kuroki, ofRickettsia tsutsugamushi isolated from a patient in Japan","volume":"28","author":"Ohashi","year":"1990","journal-title":"J Clin Microbiol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib9","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1111\/j.1348-0421.1984.tb00743.x","article-title":"Isolation ofRickettsia tsutsugamushi antigenically different from Kato, Karp, and Gilliam strains from patients","volume":"28","author":"Tamura","year":"1984","journal-title":"Microbiol Immunol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib10","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1111\/j.1348-0421.1996.tb01120.x","article-title":"Demonstration of antigenic and genotypic variation inOrienta tsutsugamushi which were isolated in Japan, and their classification into type and subtype","volume":"40","author":"Ohashi","year":"1996","journal-title":"Microbiol Immunol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib11","doi-asserted-by":"crossref","first-page":"12728","DOI":"10.1016\/S0021-9258(18)42337-X","article-title":"Diversity of immunodominant 56\u2010kDa type specific antigen (TSA) ofRickettsia\u2010Tsutsugamushi. Sequence and comparative analyses of the genes encoding TSA homologues from 4 antigenic variants","volume":"267","author":"Ohashi","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib12","first-page":"228","article-title":"Invasion and intracellular growth ofRickettsia tsutsugamushi","volume":"5","author":"Tamura","year":"1988","journal-title":"Microbiol Sci"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib13","doi-asserted-by":"crossref","first-page":"936","DOI":"10.4269\/ajtmh.2005.73.936","article-title":"Protection against scrub typhus by a plasmid vaccine encoding the 56\u2010KD outer membrane protein antigen gene","volume":"73","author":"Ni","year":"2005","journal-title":"Am J Trop Med Hyg"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib14","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1179\/136485906X112158","article-title":"Causes of acute, undifferentiated, febrile illness in rural Thailand: results of a prospective observational study","volume":"100","author":"Suttinont","year":"2006","journal-title":"Ann Trop Med Parasitol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib15","first-page":"18","article-title":"Antigenic diversity ofRickettsia tsutsugamushi: epidemiologic and ecologic significance","volume":"12","author":"Elisberg","year":"1968","journal-title":"J Hyg Epidemiol Microbiol Immunol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib16","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1574-6968.1999.tb08791.x","article-title":"Phylogenetic analysis ofOrientia tsutsugamushi strains based on the sequence homologies of 56\u2010kDa type\u2010specific antigen genes","volume":"180","author":"Enatsu","year":"1999","journal-title":"FEMS Microbiol Lett"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib17","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1128\/IAI.55.9.2290-2292.1987","article-title":"Deficiency of peptidoglycan and lipopolysaccharide components inRickettsia tsutsugamushi","volume":"55","author":"Amano","year":"1987","journal-title":"Infect Immun"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib18","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1093\/jmedent\/31.2.225","article-title":"Rickettsia tsutsugamushi in chiggers (Acari: Trombiculidae) associated with rodents in central Thailand","volume":"31","author":"Tanskul","year":"1994","journal-title":"J Med Entomol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib19","doi-asserted-by":"crossref","first-page":"299","DOI":"10.4269\/ajtmh.2003.68.299","article-title":"Short report: variation in the 56\u2010kD type\u2010specific antigen gene ofOrientia tsutsugamushi isolated from patients in Thailand","volume":"68","author":"Kollars","year":"2003","journal-title":"Am J Trop Med Hyg"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib20","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1128\/JCM.35.11.2715-2727.1997","article-title":"Laboratory diagnosis of rickettsioses: current approaches to the diagnosis of old and new rickettsial diseases","volume":"35","author":"La Scola","year":"1997","journal-title":"J Clin Microbiol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib21","doi-asserted-by":"crossref","first-page":"351","DOI":"10.4269\/ajtmh.2004.70.351","article-title":"Development of a quantitative real\u2010time polymerase chain reaction assay specific forOrientia tsutsugamushi","volume":"70","author":"Jiang","year":"2004","journal-title":"Am J Trop Med Hyg"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib22","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI\u2010BLAST: a new generation of protein database search programs","volume":"25","author":"Altschul","year":"1997","journal-title":"Nucleic Acids Res"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib23","doi-asserted-by":"crossref","first-page":"4673","DOI":"10.1093\/nar\/22.22.4673","article-title":"CLUSTAL\u2003W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position\u2010specific gap penalties and weight matrix choice","volume":"22","author":"Thompson","year":"1994","journal-title":"Nucleic Acids Res"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib24","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1093\/bib\/5.2.150","article-title":"MEGA3: integrated software for molecular evolutionary genetics analysis and sequence alignment","volume":"5","author":"Kumar","year":"2004","journal-title":"Brief Bioinform"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib25","first-page":"164","article-title":"PHYLIP\u2014Phylogeny Inference Package (version 3.2)","volume":"5","author":"Felsenstein","year":"1989","journal-title":"Cladistics"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib26","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/j.1348-0421.2003.tb03420.x","article-title":"Phylogenetic characterization ofOrientia tsutsugamushi isolated in Taiwan according to the sequence homologies of 56\u2010kDa type\u2010specific antigen genes","volume":"47","author":"Qiang","year":"2003","journal-title":"Microbiol Immunol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib27","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1111\/j.1348-0421.2001.tb02643.x","article-title":"Epidemiological survey ofOrientia tsutsugamushi distribution in field rodents in Saitama Prefecture, Japan, and discovery of a new type","volume":"45","author":"Tamura","year":"2001","journal-title":"Microbiol Immunol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib28","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S0140-6736(96)02501-9","article-title":"Scrub typhus infections poorly responsive to antibiotics in northern Thailand","volume":"348","author":"Watt","year":"1996","journal-title":"Lancet"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib29","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1128\/IAI.48.3.671-675.1985","article-title":"Analysis of polypeptide composition and antigenic components ofRickettsia tsutsugamushi by polyacrylamide gel electrophoresis and immunoblotting","volume":"48","author":"Tamura","year":"1985","journal-title":"Infect Immun"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib30","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1128\/IAI.58.7.2076-2084.1990","article-title":"The 56\u2010kilodalton major protein antigen ofRickettsia tsutsugamushi\u2014molecular cloning and sequence analysis of the Sta56 gene and precise identification of a strain\u2010specific epitope","volume":"58","author":"Stover","year":"1990","journal-title":"Infect Immun"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib31","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.diagmicrobio.2006.01.014","article-title":"Determination and geographic distribution ofOrientia tsutsugamushi serotypes in Thailand by nested polymerase chain reaction","volume":"55","author":"Manosroi","year":"2006","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib32","series-title":"Rickettsiae and rickettsial diseases at the turn of the third millenium","first-page":"67","article-title":"Genetic diversity ofOrientia tsutsugamushi","author":"Tamura","year":"1999"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib33","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.3201\/eid1210.051697","article-title":"Scrub typhus in Himalayas","volume":"12","author":"Majahan","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib34","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1348-0421.2000.tb02484.x","article-title":"Isolation ofOrientia tsutsugamushi fromLeptotrombidium fuji and its characterization","volume":"44","author":"Tamura","year":"2000","journal-title":"Microbiol Immunol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib35","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1111\/j.1348-0421.2005.tb03738.x","article-title":"Analysis of cellular fatty acids inOrientia tsutsugamushi as taxonomic markers","volume":"49","author":"Shim","year":"2005","journal-title":"Microbiol Immunol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib36","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1574-6968.1997.tb10406.x","article-title":"T\u2010track PCR fingerprinting for the rapid detection of genetic polymorphism","volume":"152","author":"Seong","year":"1997","journal-title":"FEMS Microbiol Lett"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib37","first-page":"21","article-title":"Typing ofR.\u2003tsutsugamushi isolated in Shanxi province and determination of nucleotide sequence encoding 56\u2010kDa protein gene","volume":"14","author":"Chen","year":"1998","journal-title":"Chin J Zoonoses"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib38","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1128\/JCM.31.3.598-605.1993","article-title":"High\u2010level expression of a 56\u2010kilodalton protein gene (bor56) ofRickettsia tsutsugamushi boryong and its application to enzyme\u2010linked immunosorbent assays","volume":"31","author":"Kim","year":"1993","journal-title":"J Clin Microbiol"},{"key":"10.1111\/j.1469-0691.2007.01889.x_bib39","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S0140-6736(49)90996-4","article-title":"Isolation of the Karp strain ofRickettsia tsutsugamushi","volume":"ii","author":"Derrick","year":"1949","journal-title":"Lancet"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X14633425?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X14633425?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T14:25:54Z","timestamp":1636467954000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X14633425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["S1198743X14633425"],"URL":"https:\/\/doi.org\/10.1111\/j.1469-0691.2007.01889.x","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2008,2]]}}}