{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T20:59:19Z","timestamp":1793134759001,"version":"4.5.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,11,29]],"date-time":"2014-11-29T00:00:00Z","timestamp":1417219200000},"content-version":"vor","delay-in-days":1247,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2011,7]]},"DOI":"10.1111\/j.1469-0691.2010.03394.x","type":"journal-article","created":{"date-parts":[[2010,10,14]],"date-time":"2010-10-14T12:51:26Z","timestamp":1287060686000},"page":"1078-1083","source":"Crossref","is-referenced-by-count":102,"title":["Mortality in enterococcal bloodstream infections increases with inappropriate antimicrobial therapy"],"prefix":"10.1016","volume":"17","author":[{"given":"M.","family":"Suppli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Aabenhus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.B.","family":"Harboe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.P.","family":"Andersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Tvede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-U. S.","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/j.1469-0691.2010.03394.x_bib1","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s00134-001-1143-z","article-title":"Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study","volume":"28","author":"Alberti","year":"2002","journal-title":"Intensive Care Med"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib2","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/S0196-6553(99)70031-3","article-title":"System report, data summary from January 1990\u2010May 1999, issued June 1999","volume":"27","author":"National Nosocomial Infections Surveillance (NNIS)","year":"1999","journal-title":"Am J Infect Control"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib3","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1086\/421946","article-title":"Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study","volume":"39","author":"Wisplinghoff","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib4","first-page":"4175","article-title":"Hospital\u2010acquired bacteraemia and fungaemia. A regional study with national implications","volume":"169","author":"Schonheyder","year":"2007","journal-title":"Ugeskr Laeger"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib6","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1097\/00005792-199507000-00003","article-title":"An analysis of 110 serious enterococcal infections. Epidemiology, antibiotic susceptibility, and outcome","volume":"74","author":"Patterson","year":"1995","journal-title":"Medicine (Baltimore)"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib7","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0732-8893(98)00148-5","article-title":"Vancomycin\u2010resistant enterococci: the clinical effect of a common nosocomial pathogen","volume":"33","author":"Linden","year":"1999","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib8","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0196-6553(89)90001-1","article-title":"Hospital stay and mortality attributed to nosocomial enterococcal bacteremia: a controlled study","volume":"17","author":"Landry","year":"1989","journal-title":"Am J Infect Control"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib9","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1093\/clinids\/13.4.600","article-title":"Enterococcal bacteremia: to treat or not to treat, a reappraisal","volume":"13","author":"Hoge","year":"1991","journal-title":"Rev Infect Dis"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib10","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s15010-004-2036-1","article-title":"Risk factors for infective endocarditis in patients with enterococcal bacteremia: a case\u2010control study","volume":"32","author":"Anderson","year":"2004","journal-title":"Infection"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib11","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1046\/j.1365-2796.1998.00379.x","article-title":"The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection","volume":"244","author":"Leibovici","year":"1998","journal-title":"J Intern Med"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib12","first-page":"557","article-title":"Mortality associated with enterococcal bacteremia","volume":"160","author":"Bryan","year":"1985","journal-title":"Surg Gynecol Obstet"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib13","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1086\/501624","article-title":"Enterococcal bacteremia: risk factors for vancomycin resistance and predictors of mortality","volume":"20","author":"Lautenbach","year":"1999","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib14","doi-asserted-by":"crossref","first-page":"484","DOI":"10.7326\/0003-4819-135-7-200110020-00007","article-title":"Determinants of vancomycin resistance and mortality rates in enterococcal bacteremia. a prospective multicenter study","volume":"135","author":"Vergis","year":"2001","journal-title":"Ann Intern Med"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib15","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1086\/341977","article-title":"Association between the presence of enterococcal virulence factors gelatinase, hemolysin, and enterococcal surface protein and mortality among patients with bacteremia due to Enterococcus faecalis","volume":"35","author":"Vergis","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib16","series-title":"Manual of clinical microbiology","first-page":"470","article-title":"Enterococcus","author":"Teixeira","year":"2007"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib17","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J Chronic Dis"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib18","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1378\/chest.101.6.1481","article-title":"The ACCP\u2010SCCM consensus conference on sepsis and organ failure","volume":"101","author":"Bone","year":"1992","journal-title":"Chest"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib19","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1177\/0163278703255230","article-title":"An overview of variance inflation factors for sample\u2010size calculation","volume":"26","author":"Hsieh","year":"2003","journal-title":"Eval Health Prof"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib20","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/S0197-2456(00)00104-5","article-title":"Sample\u2010size calculations for the Cox proportional hazards regression model with nonbinary covariates","volume":"21","author":"Hsieh","year":"2000","journal-title":"Control Clin Trials"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib21","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1378\/chest.118.1.146","article-title":"The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting","volume":"118","author":"Ibrahim","year":"2000","journal-title":"Chest"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib22","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1378\/chest.115.2.462","article-title":"Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients","volume":"115","author":"Kollef","year":"1999","journal-title":"Chest"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib23","first-page":"457","article-title":"Aminoglycosides therapy in patients with bacteraemia","volume":"170","author":"Freundlich","year":"2008","journal-title":"Ugeskr Laeger"},{"key":"10.1111\/j.1469-0691.2010.03394.x_bib5","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/1471-2334-6-145","article-title":"Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infections due to enterococci","volume":"6","author":"Bar","year":"2006","journal-title":"BMC Infect Dis"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X14613938?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X14613938?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,5]],"date-time":"2019-06-05T09:43:45Z","timestamp":1559727825000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X14613938"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":23,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["S1198743X14613938"],"URL":"https:\/\/doi.org\/10.1111\/j.1469-0691.2010.03394.x","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,7]]}}}