{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:59:44Z","timestamp":1789664384913,"version":"4.0.1"},"reference-count":66,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,11,30]],"date-time":"2014-11-30T00:00:00Z","timestamp":1417305600000},"content-version":"vor","delay-in-days":1278,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1111\/j.1469-0691.2011.03555.x","type":"journal-article","created":{"date-parts":[[2011,4,25]],"date-time":"2011-04-25T05:28:28Z","timestamp":1303709308000},"page":"806-814","source":"Crossref","is-referenced-by-count":119,"title":["Guidelines on interferon-\u03b3 release assays for tuberculosis infection: concordance, discordance or confusion?"],"prefix":"10.1016","volume":"17","author":[{"given":"C.M.","family":"Denkinger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Dheda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Pai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/j.1469-0691.2011.03555.x_bib1","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1056\/NEJM199910143411602","article-title":"Exogenous reinfection as a cause of recurrent tuberculosis after curative treatment","volume":"341","author":"van Rie","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib2","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1056\/NEJMoa012972","article-title":"Changes in the transmission of tuberculosis in New York City from 1990 to 1999","volume":"346","author":"Geng","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib3","first-page":"1370","article-title":"Die Allergieprobe zur Diagnose der Tuberkulose im Kindesalter","volume":"57","author":"von Pirquet","year":"1907","journal-title":"Wien Med Wochenschr"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib4","first-page":"S64","article-title":"Session 9 guidelines; section: guidelines on IGRAs: concordant or discordant","volume":"14","author":"Pai","year":"2010","journal-title":"Int J Tuberc Lung Dis [Symposium Supplement.]"},{"issue":"RR\u20105","key":"10.1111\/j.1469-0691.2011.03555.x_bib5","first-page":"1","article-title":"Updated guidelines for using interferon gamma release assays to detect Mycobacterium tuberculosis infection \u2013 United States, 2010","volume":"59","author":"Mazurek","year":"2010","journal-title":"MMWR Recomm Rep"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib6","series-title":"Red Book: 2009 report of the committee on infectious diseases","first-page":"680","article-title":"American Academy of Pediatrics. Tuberculosis","author":"Pickering","year":"2009"},{"issue":"ASC\u20105","key":"10.1111\/j.1469-0691.2011.03555.x_bib7","first-page":"1","article-title":"Interferon gamma release assays for latent tuberculosis infection. An Advisory Committee Statement (ACS)","volume":"36","author":"Canadian Tuberculosis Committee","year":"2010","journal-title":"Can Commun Dis Rep (Releve des maladies transmissibles au Canada)"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib8","series-title":"Clinical guideline 117. Tuberculosis: clinical diagnosis and management of tuberculosis, and measures for its prevention and control","author":"National Institute for Health and Clinical Excellence","year":"2011"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib9","author":"Minist\u00e9rio da Sa\u00fade"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib10","author":"Bach\u2010Nga"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib11","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.arbres.2010.02.010","article-title":"Consensus document on the diagnosis, treatment and prevention of tuberculosis","volume":"46","author":"Gonzalez\u2010Martin","year":"2010","journal-title":"Arch Bronconeumol"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib12","author":"Ministero della Salute de Italia"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib13","author":"Ministero della Salute"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib14","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1055\/s-2007-959219","article-title":"Recommendations for background studies in tuberculosis","volume":"61","author":"Diel","year":"2007","journal-title":"Pneumologie (Stuttgart, Germany)"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib15","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1055\/s-0029-1214673","article-title":"Recommendations for tuberculosis screening before initiation of TNF\u2010alpha\u2010inhibitor treatment in rheumatic diseases","volume":"63","author":"Diel","year":"2009","journal-title":"Pneumologie (Stuttgart, Germany)"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib16","series-title":"Guidelines for the diagnosis of latent tuberculosis in canton Vienna; personal communications with Beatrix Schmidgruber","author":"Schmidgruber","year":"2011"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib17","author":"Ministerio da Sa\u00fade"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib18","author":"National TB Advisory Committee"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib19","author":"Swiss Lung Association"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib20","author":"van Altena"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib21","author":"Dansk Lungemedicinsk Selskab"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib22","author":"Norwegian Institute of Public Health"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib23","author":"Ruutu"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib24","series-title":"Recommendation of Czech Thoracic Society for QuantiFERON\u2010TB Gold test \u2013 personal communication with Ludek Trnka","author":"Czech Thoracic Society","year":"2005"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib25","author":"Slovakian Ministry of Health"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib26","first-page":"51","article-title":"Zalecenia post\u0119powania w zapobieganiu i leczeniu gru\u017alicy u chorych leczonych antagonistami TNF\u2010\u03b1 (Recommendations for prophylaxis and management of tuberculosis in patients treated with TNF\u2010\u03b1 antagonists)","volume":"46","author":"Kucharz","year":"2008","journal-title":"Reumatologia"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib27","series-title":"Guidelines for the diagnosis of latent tuberculosis in Bulgaria; personal communications with Roumiana Markova","author":"Markova","year":"2011"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib28","series-title":"Guidelines for the diagnosis of latent tuberculosis in Croatia; personal communications with Vera Katalinic\u2010Jankovic","author":"Katalinic\u2010Jankovic","year":"2011"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib29","doi-asserted-by":"crossref","first-page":"38","DOI":"10.4103\/0256-4947.59373","article-title":"Saudi guidelines for testing and treatment of latent tuberculosis infection","volume":"30","author":"Al Jahdali","year":"2010","journal-title":"Ann Saudi Med"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib30","author":"National Tuberculosis Advisory Committee Australia"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib31","doi-asserted-by":"crossref","first-page":"421","DOI":"10.5694\/j.1326-5377.2009.tb02489.x","article-title":"The Australasian Society for Infectious Diseases guidelines for the diagnosis, management and prevention of infections in recently arrived refugees: an abridged outline","volume":"190","author":"Murray","year":"2009","journal-title":"Med J Aust"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib32","author":"Tymms"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib33","series-title":"Draft of updated guidelines for the diagnosis of latent tuberculosis in South Korea; personal communications with Tae Sun Shim","author":"Shim","year":"2011"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib34","first-page":"477","article-title":"Management of tuberculosis within medical facilities","volume":"85","author":"Japanese Society for Tuberculosis Prevention Committee","year":"2010","journal-title":"Kekkaku"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib35","author":"World Health Organization"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib36","author":"World Health Organization"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib37","author":"European Center for Disease Prevention and Control"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib38","doi-asserted-by":"crossref","DOI":"10.1093\/infdis\/jir410","article-title":"Interferon\u2010gamma release assays for active pulmonary TB diagnosis in adults in low\u2010 and middle\u2010income countries: systematic review and meta\u2010analysis","author":"Metcalfe","year":"2011","journal-title":"J Infect Dis"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib39","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1183\/09031936.00114810","article-title":"Interferon\u2010gamma release assays for the diagnosis of active tuberculosis: a systematic review and meta\u2010analysis","volume":"37","author":"Sester","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib40","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S1473-3099(08)70182-8","article-title":"Paediatric tuberculosis","volume":"8","author":"Newton","year":"2008","journal-title":"Lancet Infect Dis"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib41","doi-asserted-by":"crossref","DOI":"10.1183\/09031936.00181610","article-title":"Are interferon\u2010gamma release assays useful for active tuberculosis in a high\u2010burden setting?","author":"Ling","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib42","doi-asserted-by":"crossref","DOI":"10.1093\/infdis\/jir410","article-title":"Interferon\u2010gamma release assays for active pulmonary TB diagnosis in adults in low\u2010 and middle\u2010income countries: systematic review and meta\u2010analysis","author":"Metcalfe","year":"2011","journal-title":"J Infect Dis"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib43","doi-asserted-by":"crossref","DOI":"10.5588\/ijtld.10.0631","article-title":"Interferon\u2010gamma release assays and childhood tuberculosis: systematic review and meta\u2010analysis","author":"Mandalakas","year":"2011","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib44","doi-asserted-by":"crossref","first-page":"340","DOI":"10.7326\/0003-4819-146-5-200703060-00006","article-title":"Meta\u2010analysis: new tests for the diagnosis of latent tuberculosis infection: areas of uncertainty and recommendations for research","volume":"146","author":"Menzies","year":"2007","journal-title":"Ann Intern Med"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib45","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s10156-009-0686-8","article-title":"Usefulness of interferon\u2010gamma release assays for diagnosing TB infection and problems with these assays","volume":"15","author":"Mori","year":"2009","journal-title":"J Infect Chemother"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib46","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/S1473-3099(04)01206-X","article-title":"Interferon\u2010gamma assays in the immunodiagnosis of tuberculosis: a systematic review","volume":"4","author":"Pai","year":"2004","journal-title":"Lancet Infect Dis"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib47","doi-asserted-by":"crossref","first-page":"777","DOI":"10.7326\/0003-4819-149-11-200812020-00248","article-title":"Prognostic value of a T\u2010cell\u2010based, interferon\u2010gamma biomarker in children with tuberculosis contact","volume":"149","author":"Bakir","year":"2008","journal-title":"Ann Intern Med"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib48","doi-asserted-by":"crossref","first-page":"e8257","DOI":"10.1371\/journal.pone.0008257","article-title":"IFN\u2010gamma response to Mycobacterium tuberculosis, risk of infection and disease in household contacts of tuberculosis patients in Colombia","volume":"4","author":"del Corral","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib49","doi-asserted-by":"crossref","first-page":"e1379","DOI":"10.1371\/journal.pone.0001379","article-title":"Incidence of tuberculosis and the predictive value of ELISPOT and Mantoux tests in Gambian case contacts","volume":"3","author":"Hill","year":"2008","journal-title":"PLoS ONE"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib50","doi-asserted-by":"crossref","first-page":"e10508","DOI":"10.1371\/journal.pone.0010508","article-title":"Evaluation of the prognostic value of IFN\u2010gamma release assay and tuberculin skin test in household contacts of infectious tuberculosis cases in Senegal","volume":"5","author":"Lienhardt","year":"2010","journal-title":"PLoS ONE"},{"issue":"3","key":"10.1111\/j.1469-0691.2011.03555.x_bib51","doi-asserted-by":"crossref","first-page":"e17984","DOI":"10.1371\/journal.pone.0017984","article-title":"The tuberculin skin test versus QuantiFERON TB Gold\u00ae in predicting tuberculosis disease in an adolescent cohort study in South Africa","volume":"6","author":"Mahomed","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib52","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/nrmicro2236-c1","article-title":"Spectrum of latent tuberculosis \u2013 existing tests cannot resolve the underlying phenotypes","volume":"8","author":"Pai","year":"2010","journal-title":"Nat Rev Microbiol"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib53","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1016\/S0140-6736(10)60359-5","article-title":"Biomarkers and diagnostics for tuberculosis: progress, needs, and translation into practice","volume":"375","author":"Wallis","year":"2010","journal-title":"Lancet"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib54","first-page":"498","article-title":"Thinking in three dimensions: a web\u2010based algorithm to aid the interpretation of tuberculin skin test results","volume":"12","author":"Menzies","year":"2008","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib55","doi-asserted-by":"crossref","first-page":"e1001012","DOI":"10.1371\/journal.pmed.1001012","article-title":"The BCG World Atlas: a database of global BCG vaccination policies and practices","volume":"8","author":"Zwerling","year":"2011","journal-title":"PLoS Med"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib56","doi-asserted-by":"crossref","first-page":"e8517","DOI":"10.1371\/journal.pone.0008517","article-title":"Within\u2010subject variability of interferon\u2010gamma assay results for tuberculosis and boosting effect of tuberculin skin testing: a systematic review","volume":"4","author":"van Zyl\u2010Smit","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib57","doi-asserted-by":"crossref","DOI":"10.1097\/INF.0b013e318214b915","article-title":"The utility of an interferon gamma release assay for diagnosis of latent tuberculosis infection and disease in children: a systematic review and meta\u2010analysis","author":"Machingaidze","year":"2011","journal-title":"Pediatr Infect Dis J"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib58","doi-asserted-by":"crossref","first-page":"123","DOI":"10.7326\/0003-4819-126-2-199701150-00005","article-title":"Incidence of tuberculosis in the United States among HIV\u2010infected persons. The pulmonary complications of HIV Infection Study Group","volume":"126","author":"Markowitz","year":"1997","journal-title":"Ann Intern Med"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib59","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/QAI.0b013e31820b07ab","article-title":"Interferon\u2010gamma release assays for the diagnosis of latent tuberculosis infection in HIV\u2010infected individuals: a systematic review and meta\u2010analysis","volume":"56","author":"Cattamanchi","year":"2011","journal-title":"J Acquir Immune Defic Syndr"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib60","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1056\/NEJMoa011110","article-title":"Tuberculosis associated with infliximab, a tumor necrosis factor alpha\u2010neutralizing agent","volume":"345","author":"Keane","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib61","doi-asserted-by":"crossref","DOI":"10.1097\/BOR.0b013e3283474d62","article-title":"Interferon\u2010gamma release assays for diagnosis of latent tuberculosis infection: evidence in immune\u2010mediated inflammatory disorders","author":"Smith","year":"2011","journal-title":"Curr Opin Rheumatol"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib62","first-page":"43","article-title":"The risk and prevention of tuberculosis: screening strategies to detect latent tuberculosis among rheumatoid arthritis patients who use biologic therapy","volume":"8","author":"Winthrop","year":"2010","journal-title":"Int J Adv Rheumatol"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib63","doi-asserted-by":"crossref","first-page":"971","DOI":"10.7326\/0003-4819-130-12-199906150-00004","article-title":"A molecular epidemiologic analysis of tuberculosis trends in San Francisco, 1991\u20131997","volume":"130","author":"Jasmer","year":"1999","journal-title":"Ann Intern Med"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib64","article-title":"Interferon\u2010gamma release assays for tuberculosis screening of healthcare workers: a systematic review","author":"Zwerling","year":"2011","journal-title":"Thorax"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib65","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1136\/bmj.39500.677199.AE","article-title":"Grading quality of evidence and strength of recommendations for diagnostic tests and strategies","volume":"336","author":"Schunemann","year":"2008","journal-title":"BMJ"},{"key":"10.1111\/j.1469-0691.2011.03555.x_bib66","first-page":"1045","article-title":"Quality of tuberculosis guidelines: urgent need for improvement","volume":"14","author":"Gallardo","year":"2010","journal-title":"Int J Tuberc Lung Dis"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X14619741?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X14619741?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,6,18]],"date-time":"2020-06-18T16:05:17Z","timestamp":1592496317000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X14619741"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":66,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S1198743X14619741"],"URL":"https:\/\/doi.org\/10.1111\/j.1469-0691.2011.03555.x","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}