{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T07:22:24Z","timestamp":1789975344103,"version":"4.0.1"},"reference-count":96,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,11,8]],"date-time":"2011-11-08T00:00:00Z","timestamp":1320710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Child Psychology Psychiatry"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p>\n                    It was hoped that diagnostic guidelines for, and treatment of, child psychiatric disorders in\n                    <jats:italic>DSM\u20105<\/jats:italic>\n                    would be informed by the wealth of clinical genetic research related to neurodevelopmental disorders. In spite of remarkable advances in genetic technology, this has not been the case. Candidate gene, genome\u2010wide association, and rare copy number variant (CNV) studies have been carried out for attention\u2010deficit\/hyperactivity disorder (ADHD), Autism, Tourette\u2019s Syndrome, and schizophrenia, with intriguing results, but environmental factors, incomplete penetrance, pleiotropy, and genetic heterogeneity, underlying any given phenotype have limited clinical translation. One promising approach may be the use of developmental brain imaging measures as more relevant phenotypes. 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