{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T21:43:52Z","timestamp":1784756632327,"version":"3.55.0"},"reference-count":14,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2008,9,17]],"date-time":"2008-09-17T00:00:00Z","timestamp":1221609600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2008,10]]},"abstract":"<jats:p>This article reports on a female infant with Aicardi syndrome presenting with malignant migrating partial seizures from her first day of life. Initially, unilateral tonic seizures were seen with contralateral ictal electroencephalogram findings. Typically, these tonic seizures were accompanied by head and eye deviation and were followed by a tonic seizure on the other side of the body. At 6 months of age she developed epileptic spasms. She showed no motor development, did not respond to eye contact, and was nasogastric tube\u2010fed. The epilepsy syndrome in this child is refractory to antiepileptic treatment and there is no psychomotor development. This case expands the phenotype of this catastrophic epileptic encephalopathy and suggests that the corpus callosum is not necessary for the \u2018migration\u2019 of partial seizures in this syndrome.<\/jats:p>","DOI":"10.1111\/j.1469-8749.2008.03091.x","type":"journal-article","created":{"date-parts":[[2009,6,23]],"date-time":"2009-06-23T07:17:16Z","timestamp":1245741436000},"page":"790-792","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Malignant migrating partial seizures in Aicardi syndrome"],"prefix":"10.1111","volume":"50","author":[{"given":"Bosanka","family":"Jocic\u2010Jakubi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lieven","family":"Lagae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,9,17]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1995.tb00961.x"},{"key":"e_1_2_6_3_2","first-page":"65","volume-title":"Epileptic syndromes in infancy, childhood and adolescence","author":"Dulac O","year":"2002"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2005.05.002"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2004.05.001"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(99)00108-4"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1090-3798(99)91099-1"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-1211(01)00197-8"},{"key":"e_1_2_6_9_2","first-page":"609","article-title":"A new syndrome: spasm in flexion, callosal agenesis, ocular abnormalities","volume":"19","author":"Aicardi J","year":"1965","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"e_1_2_6_10_2","first-page":"211","volume-title":"Dysplasias of cerebral cortex and epilepsy","author":"Aicardi J","year":"1996"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2005.06.011"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2005.34104.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-924486"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/088307380001501102"},{"key":"e_1_2_6_15_2","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1684\/epd.2007.0055","article-title":"Pronounced microcephaly in a patient with malignant migrating partial seizures in infancy","volume":"9","author":"Hahn A","year":"2007","journal-title":"Epileptic Disord"}],"container-title":["Developmental Medicine &amp; Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1469-8749.2008.03091.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1469-8749.2008.03091.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T08:21:39Z","timestamp":1739175699000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1469-8749.2008.03091.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,17]]},"references-count":14,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["10.1111\/j.1469-8749.2008.03091.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1469-8749.2008.03091.x","archive":["Portico"],"relation":{},"ISSN":["0012-1622","1469-8749"],"issn-type":[{"value":"0012-1622","type":"print"},{"value":"1469-8749","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,17]]},"assertion":[{"value":"2008-09-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}