{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:39:38Z","timestamp":1790894378408,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,12,27]],"date-time":"2011-12-27T00:00:00Z","timestamp":1324944000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:p><jats:bold>Aim\u2002<\/jats:bold> In individuals with cerebral palsy (CP), cerebral insults during early development may induce profound reorganization of the motor representation. This study determined the extent of alterations in cortical somatosensory functions in adolescents with hemiplegic CP with subcortical brain lesions.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> We recorded somatosensory evoked magnetic fields in response to hand area stimulation from eight adolescents with hemiplegic CP (five females and three males; mean age 14y 6mo, SD 2y 3mo) and eight age\u2010 and sex\u2010matched healthy comparison adolescents (mean age 15y 4mo, SD 2y 4mo). All participants in the CP group had purely subcortical brain lesions in magnetic resonance images.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> The somatosensory representation of the affected limb was contralateral (i.e. ipsilesional), but detailed inspection of the evoked responses showed alterations bilaterally. In the primary somatosensory cortex, the representation areas of digits II and V were in both hemispheres closer to each other in participants with CP than in comparison participants [ANOVA main effect group <jats:italic>F<\/jats:italic><jats:sub>1,14<\/jats:sub>=5.58; <jats:italic>p<\/jats:italic>=0.03]. In addition, the morphology of median nerve evoked fields was altered in the participants with CP.<\/jats:p><jats:p><jats:bold>Interpretation\u2002<\/jats:bold> In hemiplegic CP, modification of the somatosensory cortical network extends beyond what would be expected based on the unilateral symptoms and the anatomical lesion. Further understanding of the functional alterations in the sensorimotor networks may aid in developing more precisely designed rehabilitation strategies.<\/jats:p>","DOI":"10.1111\/j.1469-8749.2011.04165.x","type":"journal-article","created":{"date-parts":[[2011,12,27]],"date-time":"2011-12-27T09:25:19Z","timestamp":1324977919000},"page":"361-367","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Bilateral alterations in somatosensory cortical processing in hemiplegic cerebral palsy"],"prefix":"10.1111","volume":"54","author":[{"given":"P\u00c4IVI","family":"NEVALAINEN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ELINA","family":"PIHKO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HELENA","family":"M\u00c4ENP\u00c4\u00c4","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LEENA","family":"VALANNE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LAURI","family":"NUMMENMAA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LEENA","family":"LAURONEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,12,27]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2000.tb00695.x"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20297"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf227"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2007.02.014"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000227937.49151.fd"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ar.10069"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2009.03306.x"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2007.10.006"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1103\/RevModPhys.65.413"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2006.tb01313.x"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/51\/7\/008"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.06.041"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1991.66.3.1048"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/378071a0"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.8.3593"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/375482a0"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.10049"},{"key":"e_1_2_8_19_2","first-page":"101","article-title":"Does the P35m SEF deflection really come from the motor cortex?","volume":"104","author":"Huttunen J","year":"1997","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.10.1889"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199811160-00006"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/77.3.269"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/6.2.196"},{"key":"e_1_2_8_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199512150-00033"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200101)49:1<90::AID-ANA12>3.0.CO;2-D"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000166027.81432.9B"}],"container-title":["Developmental Medicine &amp; 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