{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T08:15:38Z","timestamp":1794557738605,"version":"4.9.1"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,3,12]],"date-time":"2012-03-12T00:00:00Z","timestamp":1331510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p><jats:bold>Aim\u2002<\/jats:bold> Achondroplasia is characterized by delays in the development of communication and motor skills. While previously reported developmental profiles exist across gross motor, fine motor, feeding, and communication skills, there has been no prospective study of development across multiple areas simultaneously.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> This Australasian population\u2010based study utilized a prospective questionnaire to quantify developmental data for skills in children born from 2000 to 2009. Forty\u2010eight families from Australia and New Zealand were asked to report every 3\u2003months on their child\u2019s attainment of 41 milestones. Results include reference to previously available prospective information.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Information from questionnaires was used to develop an achondroplasia\u2010specific developmental recording form. The 25th, 50th, 75th, and 90th centiles were plotted to offer clear guidelines for development across gross motor, fine motor, feeding, and communication skills in children with achondroplasia.<\/jats:p><jats:p><jats:bold>Interpretations\u2002<\/jats:bold> Consistent with results from previous research, children with achondroplasia are delayed in development of gross motor and ambulatory skills. Young children with achondroplasia demonstrate a number of unique movement strategies that appear compensatory for the biomechanical changes. While delays were seen in development of later communication items, there were fewer delays seen across development of early communication, fine motor, and feeding skills.<\/jats:p>","DOI":"10.1111\/j.1469-8749.2012.04234.x","type":"journal-article","created":{"date-parts":[[2012,3,12]],"date-time":"2012-03-12T16:00:30Z","timestamp":1331568030000},"page":"532-537","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":69,"title":["Development in children with achondroplasia: a prospective clinical cohort study"],"prefix":"10.1111","volume":"54","author":[{"given":"PENELOPE J","family":"IRELAND","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SAMANTHA","family":"DONAGHEY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JAMES","family":"McGILL","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANDREAS","family":"ZANKL","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ROBERT S","family":"WARE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"VERITY","family":"PACEY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JENNY","family":"AULT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RAVI","family":"SAVARIRAYAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DAVID","family":"SILLENCE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ELIZABETH","family":"THOMPSON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SHARRON","family":"TOWNSHEND","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LEANNE M","family":"JOHNSTON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,3,12]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32485"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004703-199706000-00001"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320410215"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/DBP.0b013e3181c72052"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19990416)88:2<145::AID-AJMG10>3.0.CO;2-B"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320090105"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-1440"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004694-200007000-00004"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004310000505"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.DBP.0000267554.96081.12"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(88)80157-4"},{"key":"e_1_2_8_13_2","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1542\/peds.95.3.443","article-title":"Health supervision for children with achondroplasia","volume":"95","author":"American Academy of Pediatrics Committee on Genetics","year":"1995","journal-title":"Pediatrics"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.89.1.91"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320470540"},{"key":"e_1_2_8_16_2","volume-title":"Ages and Stages Questionnaires (3rd edn, ASQ\u20103)","author":"Squires J","year":"2009"}],"container-title":["Developmental Medicine &amp; 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