{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:59:22Z","timestamp":1787014762508,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,3,17]],"date-time":"2012-03-17T00:00:00Z","timestamp":1331942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p>\n                    <jats:bold>Aim\u2002<\/jats:bold>\n                    The aim of this study was to determine whether constraint\u2010induced movement therapy is more effective than bimanual training in improving the quality of life of children with unilateral cerebral palsy (CP).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Method\u2002<\/jats:bold>\n                    Sixty\u2010three children (mean age 10y 2mo [SD 2y 6mo]; 33 males, 30 females) with CP of the spastic motor type (\n                    <jats:italic>n<\/jats:italic>\n                    =59) or with spasticity and dystonia (\n                    <jats:italic>n<\/jats:italic>\n                    =4) were randomly allocated to two groups. The children were assessed as Manual Ability Classification System level I (\n                    <jats:italic>n<\/jats:italic>\n                    =16), II (\n                    <jats:italic>n<\/jats:italic>\n                    =46), or III (\n                    <jats:italic>n<\/jats:italic>\n                    =1). Each group received 6\u2003hours of daily intervention (either constraint\u2010induced movement therapy [CIMT] or bimanual training [BIM]) for 10\u2003days over a 2\u2010week period (total intervention time 60h). Children aged 9\u2003years and older completed the Cerebral Palsy Quality of Life Questionnaire for Children (CPQOL\u2010Child) and those aged 8\u2003years and older completed the KIDSCREEN\u201052. All parents completed proxy versions of each measure. Assessments were made at baseline and at 3, 26, and 52\u2003weeks after the end of the intervention.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results\u2002<\/jats:bold>\n                    Thirty\u2010five children completed the CPQOL\u2010Child and 41 completed the KIDSCREEN\u201052. No changes in social or emotional well\u2010being were reported by children in either group. Children and parents from both groups reported a significant improvement in their or their child\u2019s feelings about functioning as well as participation and physical health on the CPQOL\u2010Child. The parents of children receiving CIMT reported positive and sustained changes in their child\u2019s social well\u2010being (CPQOL\u2010Child). The CIMT group showed significant improvements in physical well\u2010being, psychological well\u2010being, and moods and emotions (KIDSCREEN\u201052) at 3\u2003weeks post intervention, which were maintained over the study period.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Interpretation\u2002<\/jats:bold>\n                    Intensive goal\u2010directed upper limb training programmes using either CIMT or BIM achieved domain\u2010specific changes in quality of life relating to feelings about functioning and participation and physical health. A condition\u2010specific quality of life compared with a generic measure may be better able to detect changes in quality of life in children with unilateral CP.\n                  <\/jats:p>","DOI":"10.1111\/j.1469-8749.2012.04272.x","type":"journal-article","created":{"date-parts":[[2012,3,17]],"date-time":"2012-03-17T03:14:25Z","timestamp":1331954065000},"page":"415-423","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Impact of intensive upper limb rehabilitation on quality of life: a randomized trial in children with unilateral cerebral palsy"],"prefix":"10.1111","volume":"54","author":[{"given":"LEANNE","family":"SAKZEWSKI","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"STACEY","family":"CARLON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"NORA","family":"SHIELDS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JENNY","family":"ZIVIANI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ROBERT S","family":"WARE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ROSLYN N","family":"BOYD","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,3,17]]},"reference":[{"key":"e_1_2_9_2_2","volume-title":"Cerebral Palsies: Epidemiology and Causal Pathways","author":"Stanley F","year":"2000"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1991.tb14916.x"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.2001.00051.x"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2007.00225.x"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.02031.x"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2006.10.017"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2425"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162206000387"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-10-4"},{"key":"e_1_2_9_11_2","volume-title":"International Classification of Functioning, Disability and Health","author":"World Health Organization","year":"2001"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2010.03859.x"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2010.11.022"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03245.x"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2007.00830.x"},{"key":"e_1_2_9_16_2","volume-title":"Cerebral Palsy Quality of Life Questionnaire for Children (CP QOL\u2010Child) Manual","author":"Waters E","year":"2006"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162207000126.x"},{"key":"e_1_2_9_18_2","volume-title":"The Kidscreen Questionnaires. 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