{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T21:57:41Z","timestamp":1793743061176,"version":"4.6.1"},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,4,24]],"date-time":"2012-04-24T00:00:00Z","timestamp":1335225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:p><jats:bold>Aim\u2002<\/jats:bold> The aim of the study was to assess weight changes after traumatic brain injury (TBI) in children and the factors influencing them.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> We conducted a longitudinal observational study of children with TBI of mixed severity who were consecutively admitted to one rehabilitation department (39 children; 23 males, 16 females; median age 8y 7mo; 25th to 75th centiles 3y 7mo\u201311y 6mo). Weight and height before TBI were obtained from the children\u2019s records and were measured monthly for 1\u2003year after TBI. Body mass index (BMI) and BMI <jats:italic>z<\/jats:italic>\u2010scores were calculated, and pre\u2010TBI values were compared with the final values using paired tests. Linear mixed\u2010effect interaction models were used to assess the effect of various factors on <jats:italic>z<\/jats:italic>\u2010score evolution.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Z\u2010score curves revealed early weight loss followed by a rapid increase in weight. The mean BMI gain over the period under study was 0.9kg\/m\u00b2 (<jats:italic>p\u2003<\/jats:italic>&lt;<jats:italic>\u2003<\/jats:italic>0.001) and the mean <jats:italic>z<\/jats:italic>\u2010score gain was 0.4 (<jats:italic>p\u2003<\/jats:italic>=<jats:italic>\u2003<\/jats:italic>0.006). Six children had become overweight by the time of final assessment. Factors associated with a greater rate of increase in the post\u2010TBI <jats:italic>z<\/jats:italic>\u2010score were mobility restriction, male sex, and older age. Global pre\u2010 to post\u2010TBI weight gain was significantly higher in males (<jats:italic>z<\/jats:italic>\u2010score 0.7). Pituitary hormonal testing was available for 17 children at 3\u2003months and for 27 at 1\u2003year. Growth hormone deficiency was detected in one child.<\/jats:p><jats:p><jats:bold>Interpretation\u2002<\/jats:bold> Weight gain of children during the first year after TBI was rapid and excessive. Male sex was a risk factor for excessive weight gain.<\/jats:p>","DOI":"10.1111\/j.1469-8749.2012.04291.x","type":"journal-article","created":{"date-parts":[[2012,4,24]],"date-time":"2012-04-24T07:02:48Z","timestamp":1335250968000},"page":"624-628","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Weight gain after childhood traumatic brain injury: a matter of concern"],"prefix":"10.1111","volume":"54","author":[{"given":"CLAIRE","family":"JOURDAN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DOMINIQUE","family":"BRUGEL","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KATELYNE","family":"HUBEAUX","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HANNA","family":"TOURE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANNE","family":"LAURENT\u2010VANNIER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MATHILDE","family":"CHEVIGNARD","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,4,24]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511526879.011"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e328340296f"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2005.369ER"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1159\/000110465"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/13638490500049578"},{"key":"e_1_2_8_7_2","first-page":"76","article-title":"Child growth standards based on length\/height, weight and age","volume":"450","author":"World Health Organization","year":"2006","journal-title":"Acta Paediatr Suppl"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.07.043497"},{"key":"e_1_2_8_9_2","unstructured":"World Health Organization(2009)AnthroPlus for personal computers manual: Software for assessing growth of the world\u2019s children and adolescents. [database on the Internet]. Available from:http:\/\/www.who.int\/growthref\/tools\/en\/(accessedon March 2012)."},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.3109\/17477161003615583"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/02699050400025315"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.2307\/2529876"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.3233\/NRE-2010-0586"},{"key":"e_1_2_8_14_2","first-page":"58","article-title":"Modification in eating behaviour and weight set\u2010point in the medium term after severe brain injury","volume":"5","author":"Hamchaoui S","year":"2010","journal-title":"Clin Nutr"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2010.1408"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2007.01.010"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001530.pub2"},{"key":"e_1_2_8_18_2","volume-title":"Recommandations de la Haute Autorit\u00e9 de Sant\u00e9: Prise en charge de l\u2019ob\u00e9sit\u00e9 de l\u2019enfant et de l\u2019adolescent"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2005.02.002"},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-004-2117-y"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.1515\/JPEM.2006.19.2.121"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2001-16855"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(05)70348-5"},{"key":"e_1_2_8_24_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021797"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1177\/0009922810376234"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-0901"},{"key":"e_1_2_8_27_2","doi-asserted-by":"publisher","DOI":"10.3109\/02699059309008170"},{"key":"e_1_2_8_28_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2008.145235"},{"key":"e_1_2_8_29_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2008.147165"}],"container-title":["Developmental Medicine &amp; Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1469-8749.2012.04291.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1469-8749.2012.04291.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T01:04:53Z","timestamp":1698714293000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1469-8749.2012.04291.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,24]]},"references-count":28,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["10.1111\/j.1469-8749.2012.04291.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1469-8749.2012.04291.x","archive":["Portico"],"relation":{},"ISSN":["0012-1622","1469-8749"],"issn-type":[{"value":"0012-1622","type":"print"},{"value":"1469-8749","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,24]]},"assertion":[{"value":"2012-04-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}