{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T19:55:49Z","timestamp":1775246149263,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2003,12,22]],"date-time":"2003-12-22T00:00:00Z","timestamp":1072051200000},"content-version":"vor","delay-in-days":1085,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2001,1]]},"abstract":"<jats:p><jats:bold>Objective<\/jats:bold> To compare the results of removing mature teratoma with laparoscopy or without laparoscopy.<\/jats:p><jats:p><jats:bold>Design<\/jats:bold> A prospective, randomised trial.<\/jats:p><jats:p><jats:bold>Setting<\/jats:bold> Medical centre.<\/jats:p><jats:p><jats:bold>Participants<\/jats:bold> Seventy\u2010nine women with mature teratomas identified using results of ultrasound examinations and biochemical markers.<\/jats:p><jats:p><jats:bold>Intervention<\/jats:bold> Cystectomy with laparoscopic approach or without laparoscopic approach through a culdotomy.<\/jats:p><jats:p><jats:bold>Methods<\/jats:bold> Patients were randomly assigned to have their cysts removed via vaginal cystectomy without laparoscopy (<jats:styled-content><jats:italic>n=<\/jats:italic>37, Group A<\/jats:styled-content>) or laparoscopic cystectomy via culdotomy opening (<jats:styled-content><jats:italic>n=<\/jats:italic>42, Group B<\/jats:styled-content>). Inclusion criteria were history of vaginal delivery, no previous abdominal surgery, no history of pelvic inflammatory disease, no medical illness, and no presenting symptoms. Eight women randomised to Group A withdrew before surgery. The laparoscopically resected tumours were each put into a cellulose bag, and tumours without laparoscopic\u2010assistance were removed directly via the vagina.<\/jats:p><jats:p><jats:bold>Results<\/jats:bold> Blood loss in Group A (<jats:styled-content>88\u00b137 ml<\/jats:styled-content>) was significantly more than that in Group B (<jats:styled-content>64\u00b120 ml, P=0.000<\/jats:styled-content>). The post\u2010operative recovery times were 20 and 17 hours, respectively (<jats:styled-content>P=0.030<\/jats:styled-content>). The rates of successful surgery were 58.6 and 97.6%, respectively (<jats:styled-content>P=0.002<\/jats:styled-content>). The spillage rates were 44.8% and 19.0%, respectively (<jats:styled-content>P=0.006<\/jats:styled-content>). There were no significant differences in tumour size, patient age, and operative time between groups.<\/jats:p><jats:p><jats:bold>Conclusion<\/jats:bold> Cystectomy without assistance of laparoscopy could be applied to manage mature teratoma of the ovary; however, because of the difficulty of this technique, we had high percentages of tumour spillage and more blood loss during operation and a high percentage of patients who required conversion to laparotomy compared with laparoscopic cystectomy. We favoured laparoscopically assisted cystectomy to manage mature teratoma.<\/jats:p>","DOI":"10.1111\/j.1471-0528.2001.00003.x","type":"journal-article","created":{"date-parts":[[2003,12,22]],"date-time":"2003-12-22T18:20:21Z","timestamp":1072117221000},"page":"91-94","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Excision of mature teratoma using culdotomy, with and without laparoscopy: a prospective randomised trial"],"prefix":"10.1111","volume":"108","author":[{"given":"Peng\u2010Hui","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen\u2010Ling","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi\u2010Mou","family":"Juang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen\u2010Ying","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsiang\u2010Tai","family":"Chao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiou\u2010Chung","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,12,22]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"815","article-title":"Laparoscopic excision of ovarian dermoid cysts with controlled intraoperative spillage","volume":"44","author":"Zanetta G","year":"1999","journal-title":"J Reprod Med"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1998.5128"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-3804(99)80015-2"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(98)00224-5"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1989.tb02412.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1995.tb10868.x"},{"key":"e_1_2_6_8_2","unstructured":"SAS\/STAT User's Guide (Version 6.12.). 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