{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T23:15:48Z","timestamp":1776208548744,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2003,12,22]],"date-time":"2003-12-22T00:00:00Z","timestamp":1072051200000},"content-version":"vor","delay-in-days":689,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2002,2]]},"abstract":"<jats:p><jats:bold>Objective\n\t\t\t\t\t<\/jats:bold> To determine whether transvaginal ultrasound measurement of bladder wall thickness could replace ambulatory urodynamics when investigating women with lower urinary tract dysfunction not explained by conventional laboratory urodynamic studies.<\/jats:p><jats:p><jats:bold>Design\n\t\t\t\t\t<\/jats:bold> A blinded prospective study.<\/jats:p><jats:p><jats:bold>Setting\n\t\t\t\t\t<\/jats:bold> Tertiary referral unit in a London teaching hospital.<\/jats:p><jats:p><jats:bold>Population\n\t\t\t\t\t<\/jats:bold> One hundred and twenty\u2010eight women referred for ambulatory urodynamics with equivocal laboratory urodynamic findings or whose symptoms were not explained by the laboratory urodynamic findings.<\/jats:p><jats:p><jats:bold>Methods\n\t\t\t\t\t<\/jats:bold> Transvaginal ultrasound assessment of bladder wall thickness was performed in three planes with an empty bladder prior to ambulatory urodynamics. Mean bladder wall thickness was calculated and the results analysed with respect to the ambulatory urodynamic diagnosis.<\/jats:p><jats:p><jats:bold>Main outcome methods\n\t\t\t\t\t<\/jats:bold> Mean bladder wall thickness in women with a normal ambulatory study or a diagnosis of detrusor instability, genuine stress incontinence (GSI) or mixed incontinence.<\/jats:p><jats:p><jats:bold>Results\n\t\t\t\t\t<\/jats:bold> Using a one way analysis of variance (ANOVA) bladder wall thickness was found to be significantly different in all diagnostic groups and this reached significance (<jats:styled-content><jats:italic>P<\/jats:italic>= 0.0001<\/jats:styled-content>). There was no overlap in the 95% confidence intervals representing a diagnosis of detrusor instability or genuine stress incontinence.<\/jats:p><jats:p><jats:bold>Conclusions\n\t\t\t\t\t<\/jats:bold> Transvaginal ultrasound assessment of mean bladder wall thickness is a sensitive screening tool, which can detect detrusor instability in those women with equivocal laboratory urodynamics. In women who have no evidence of GSI on laboratory studies, a cutoff of 6.0mm is highly suggestive of detrusor instability. However, in those women with GSI then ambulatory studies probably remain the investigation of choice.<\/jats:p>","DOI":"10.1111\/j.1471-0528.2002.01021.x","type":"journal-article","created":{"date-parts":[[2003,12,22]],"date-time":"2003-12-22T16:34:07Z","timestamp":1072110847000},"page":"145-148","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":103,"title":["Can ultrasound replace ambulatory urodynamics when investigating women with irritative urinary symptoms?"],"prefix":"10.1111","volume":"109","author":[{"given":"Dudley","family":"Robinson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Anders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Cardozo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Bidmead","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Toozs\u2010Hobson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikram","family":"Khullar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,12,22]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1980.tb04443.x"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1970.tb06796.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00451709"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1991.tb15283.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0022-5347(17)37730-3","article-title":"Extramural ambulatory urodynamic monitoring during natural filling and normal daily activities: evaluation of 100 patients","volume":"146","author":"Doorn ESC","year":"1991","journal-title":"J Urol"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1994.04030220.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1996.tb09910.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1989.tb06039.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.1998.00537.x"},{"key":"e_1_2_6_11_2","first-page":"730","article-title":"Ultrasound of the bladder: a replacement for cystoscopy and bladder biopsy? [abstract]","volume":"101","author":"Khullar V","year":"1994","journal-title":"Br J Obstet Gynaecol"},{"key":"e_1_2_6_12_2","first-page":"352","article-title":"Three dimensional ultrasound of the urethra and urethral sphincter\u2014a new diagnostic technique","volume":"13","author":"Khullar V","year":"1994","journal-title":"Neurourol Urodynam"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-6777(1998)17:2<129::AID-NAU6>3.0.CO;2-F"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2000.tb13224.x"},{"key":"e_1_2_6_15_2","first-page":"S55","article-title":"Morbidity and tolerability of ambulatory urodynamics","volume":"11","author":"Pesce F","year":"2000","journal-title":"Int Urogynaecol J"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1471-0528.2002.01021.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1471-0528.2002.01021.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T18:24:01Z","timestamp":1697567041000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1471-0528.2002.01021.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,2]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2002,2]]}},"alternative-id":["10.1111\/j.1471-0528.2002.01021.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1471-0528.2002.01021.x","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,2]]},"assertion":[{"value":"2003-12-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}