{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T20:44:54Z","timestamp":1784925894123,"version":"3.55.0"},"reference-count":8,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2006,6,22]],"date-time":"2006-06-22T00:00:00Z","timestamp":1150934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2006,7]]},"abstract":"<jats:p>The aim of this randomised, double\u2010blind, placebo\u2010controlled trial was to evaluate the effectiveness of intraperitoneal instillation of bupivacaine following laparoscopy and dye test. Women received either 15 ml of 0.9% saline (<jats:italic>n<\/jats:italic>= 42) or 15 ml of 0.5% bupivacaine (<jats:italic>n<\/jats:italic>= 43), which was instilled intraperitoneally. Pain and nausea scores were recorded on a visual analogue scale (VAS). Pain perception was no different in the bupivacaine group compared with the control group with median values of VAS at 2 hours (18, 19; <jats:italic>P<\/jats:italic>= 0.8), 6 hours (21, 22; <jats:italic>P<\/jats:italic>= 0.5), 12 hours (19, 25; <jats:italic>P<\/jats:italic>= 0.8), 24 hours (27, 27; <jats:italic>P<\/jats:italic>= 0.9) and 48 hours (21, 13; <jats:italic>P<\/jats:italic>= 0.26). Women in the bupivacaine group were less nauseated than controls in the immediate postoperative period (with median VAS scores of 0, 8; <jats:italic>P<\/jats:italic> value = 0.03 at 2 hours and 0, 7; <jats:italic>P<\/jats:italic>= 0.01 at 6 hours).<\/jats:p>","DOI":"10.1111\/j.1471-0528.2006.00959.x","type":"journal-article","created":{"date-parts":[[2006,6,22]],"date-time":"2006-06-22T16:58:29Z","timestamp":1150995509000},"page":"835-838","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["A prospective double\u2010blind randomised controlled trial of intraoperative pelvic instillation with bupivacaine for management of pain following laparoscopy and dye"],"prefix":"10.1111","volume":"113","author":[{"given":"S","family":"Sripada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Mathur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Hamilton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Cranfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Bhattacharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,6,22]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200004000-00024"},{"key":"e_1_2_6_3_2","first-page":"877","article-title":"Postoperative pain after local anesthetics for laparoscopic sterilization","volume":"84","author":"Benhamou D","year":"1994","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/82.4.586"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1994.tb11924.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000127370.66704.f5"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(98)00130-7"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1145\/355732.355740"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/69.supplement_1.24S"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1471-0528.2006.00959.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1471-0528.2006.00959.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T09:31:00Z","timestamp":1697016660000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1471-0528.2006.00959.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6,22]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2006,7]]}},"alternative-id":["10.1111\/j.1471-0528.2006.00959.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1471-0528.2006.00959.x","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6,22]]},"assertion":[{"value":"2006-06-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}